MARC details
| 000 -LEADER |
|---|
| fixed length control field |
04594nam a22006017a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
210607s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
0002-9394 |
| 024 ## - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1016/j.ajo.2021.03.035 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
S0002-9394(21)00160-4 [pii] |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| PMID |
33857506 |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
New Indicator of Children's Excessive Electronic Screen Use and Factors in Meibomian Gland Atrophy. |
| 251 ## - Source |
|---|
| Source |
American Journal of Ophthalmology. 229:63-70, 2021 09. |
| 252 ## - Abbreviated Source |
|---|
| Abbreviated source |
Am J Ophthalmol. 229:63-70, 2021 09. |
| 252 ## - Abbreviated Source |
|---|
| Former abbreviated source |
Am J Ophthalmol. 2021 Apr 12 |
| 253 ## - Journal Name |
|---|
| Journal name |
American journal of ophthalmology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Manufacturer |
FY2022 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
|---|
| Publication status |
aheadofprint |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
|---|
| Publication status |
ppublish |
| 266 ## - Date added to catalog |
|---|
| Date added to catalog |
2021-06-07 |
| 268 ## - Previous citation |
|---|
| -- |
American Journal of Ophthalmology. 2021 Apr 12 |
| 269 ## - Original dates |
|---|
| Original fiscal year |
FY2021 |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
CONCLUSIONS: Children's excessive electronic-screen-use is associated with severe-meibomian-gland-atrophy. Further research is needed to establish formal electronic-screen-use limits based on meibography-grade and evaluate correlation of autoimmune-disease-biomarker-positivity in children with severe-meibomian-gland-atrophy. Copyright (c) 2021. Published by Elsevier Inc. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
DESIGN: Retrospective cross-sectional study METHODS: Children (6-17years) presenting at clinical practice December 2016-2017 were evaluated for >=grade 2 MGA versus age-matched-controls with insignificant atrophy (<grade 1 atrophy). Questionnaires assessed dry-eye symptoms, daily-electronic-screen-use-hours, diet, outdoor-time. Meibography-imaging assessed for severe-meibomian-gland-atrophy (>=grade 2 atrophy, >=1eyelid on validated, 4-point, ImageJ-scale: 0(normal)-3(severe)). Autoimmune-disease-biomarker-positivity was assessed in 16 severe-meibomian-gland-atrophy-cases after found relevant in 1 case. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
PURPOSE: To evaluate the association of children's daily-electronic-screen-use with severe meibomian-gland-atrophy (MGA). |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
RESULTS: 172 children were evaluated. Patients with known meibomian-gland-atrophy causes or poor-quality meibographies were excluded. 41 met inclusion criteria (mean-age, 11years; 49% female): 17 cases had severe-meibomian-gland-atrophy; 24 controls had insignificant gland-atrophy. All severe-meibomian-gland-atrophy cases had ocular symptoms/signs of dry-eye-disease including corneal neovascularization (29%), best-corrected-visual-acuity loss (41%), and central corneal neovascularization (14%). No controls had significant dry-eye symptoms/signs. Controls had lower/"better" meibogrades versus cases (p<0.01). In severe-meibomian-gland-atrophy cases, 86% reported >=4hours of daily-electronic-screen-use; 50% reported >=8hours. No controls exceeded 2hours. Increased electronic-screen-use was positively associated with increased/"worse" meibogrades (Odds-Ratio: 2.74; 95%CI, 1.39-5.41). In 16 severe-meibomian-gland-atrophy cases, 62.5% tested positive for autoimmune-biomarker(s) though none had systemic-symptoms: 18.8% Rheumatoid-Factor; 6.25% SSA/SSB; 31.3% early Sjogren's-syndrome-biomarkers; 6.25% ANA-positive/RF-negative. Autoimmune-disease-biomarker-positivity was not significantly associated with severe-meibomian-gland-atrophy vs controls (p=0.34, right-eye; p=0.71, left-eye). |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
*Dry Eye Syndromes |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
*Eyelid Diseases |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Atrophy |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Child |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cross-Sectional Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Electronics |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Eyelid Diseases/di [Diagnosis] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Eyelid Diseases/pa [Pathology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Male |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Meibomian Glands/dg [Diagnostic Imaging] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Meibomian Glands/pa [Pathology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Retrospective Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Tears |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
|---|
| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
|---|
| Department |
Ophthalmology |
| 657 ## - INDEX TERM--FUNCTION |
|---|
| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Martinez, Alberto |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Weber, Jacquelyn |
| 790 ## - Authors |
|---|
| All authors |
Ahn J, Cremers L, Cremers SL, Khan ARG, Kossler AL, Martinez A, Pigotti C, Weber J |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| DOI |
<a href="https://dx.doi.org/10.1016/j.ajo.2021.03.035">https://dx.doi.org/10.1016/j.ajo.2021.03.035</a> |
| Public note |
https://dx.doi.org/10.1016/j.ajo.2021.03.035 |
| -- |
https://dx.doi.org/10.1016/j.ajo.2021.03.035xl - https://dx.doi.org/10.1016/j.ajo.2021.03.035 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| DOI |
<a href="https://dx.doi.org/10.1016/j.ajo.2021.03.035xl - https://dx.doi.org/10.1016/j.ajo.2021.03.035">https://dx.doi.org/10.1016/j.ajo.2021.03.035xl - https://dx.doi.org/10.1016/j.ajo.2021.03.035</a> |
| Public note |
https://dx.doi.org/10.1016/j.ajo.2021.03.035 |
| -- |
https://dx.doi.org/10.1016/j.ajo.2021.03.035xl - https://dx.doi.org/10.1016/j.ajo.2021.03.035 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
