Nonseminomatous Germ-Cell Tumor Presenting as Bilateral Adrenal Masses. (Record no. 6393)

MARC details
000 -LEADER
fixed length control field 03834nam a22004697a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210607s20212021 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2376-0605
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.aace.2020.11.011 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC7924156 [pmc]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S2376-0605(20)31012-9 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 33851019
245 ## - TITLE STATEMENT
Title Nonseminomatous Germ-Cell Tumor Presenting as Bilateral Adrenal Masses.
251 ## - Source
Source Aace Clinical Case Reports. 7(1):43-46, 2021 Jan-Feb.
252 ## - Abbreviated Source
Abbreviated source AACE clin. case rep.. 7(1):43-46, 2021 Jan-Feb.
253 ## - Journal Name
Journal name AACE clinical case reports
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
266 ## - Date added to catalog
Date added to catalog 2021-06-07
520 ## - SUMMARY, ETC.
Abstract Conclusion: We report a rare case of rapidly progressing adrenal masses in a young man, found to have metastasized from nonseminomatous germ-cell tumors. Histopathologic confirmation of the metastatic tumor was done, which prevented unnecessary adrenalectomy. The patient received appropriate chemotherapy. Copyright (c) 2020 AACE. Published by Elsevier Inc.
520 ## - SUMMARY, ETC.
Abstract Methods: The diagnosis of the adrenal masses from the nonseminomatous germ-cell tumor of a retroperitoneal lymph node origin was based on a retroperitoneal lymph node core biopsy. An initial core biopsy of the adrenal gland revealed necrotic tissue and inflammatory cells without evidence of malignancy. Due to nondiagnostic findings, the core biopsy was repeated, which showed degenerating cells with a high mitotic index and immunohistochemical staining positive for vimentin, suggesting the possibility of a high-grade sarcoma. A retroperitoneal lymph node biopsy was performed. The patient was started on chemotherapy.
520 ## - SUMMARY, ETC.
Abstract Objective: Many tumors can metastasize to the adrenal glands, making the diagnosis of adrenal masses challenging. Awareness that rare primary tumors can metastasize to the adrenals and consideration of biopsy for their diagnosis, sometimes at extra-adrenal sites, is essential to prevent unnecessary adrenalectomies and facilitate the right treatment. We report a rare case of bilateral adrenal masses due to metastasis from a nonseminomatous germ-cell tumor of a retroperitoneal lymph node origin.
520 ## - SUMMARY, ETC.
Abstract Results: A 34-year-old man presented with acute left upper-abdominal pain of 2 weeks and tenderness on the left upper quadrant of the abdomen, and he was found to have bilateral adrenal masses. Laboratory results showed the following: adrenocorticotropic hormone 41 pg/mL (7-69 pg/mL), metanephrine <0.1 nmol/L (0-0.49 nmol/L), normetanephrine 0.99 nmol/L (0-0.89 nmol/L), and morning cortisol 3.1 mug/dL after a 1-mg dexamethasone-suppression test. His dehydroepiandrosterone sulfate level was 62 mug/dL (120-520 mug/dL), and 17OH progesterone level was 36 ng/dL (<138 ng/dL); androstenedione and serum estradiol levels were normal. Laboratory tests for tumor markers revealed the following: testosterone 21 ng/dL (241-827 ng/dL), prostate-specific antigen 0.57 ng/mL (0-4 ng/mL), alpha-fetoprotein 1.9 IU/mL (0.6-6 IU/ml), and beta-human chorionic gonadotropin 134 mIU/mL (0-1 mIU/mL).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Cardiovascular Disease Fellowship
656 ## - INDEX TERM--OCCUPATION
Department Endocrinology Fellowship
656 ## - INDEX TERM--OCCUPATION
Department Medicine/Endocrinology
656 ## - INDEX TERM--OCCUPATION
Department Medicine/Nuclear Medicine
656 ## - INDEX TERM--OCCUPATION
Department Pathology
657 ## - INDEX TERM--FUNCTION
Medline publication type Case Reports
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Baral, Neelam
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Basyal, Binaya
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Kulkarni, Kanchan
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Lee, Wen
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Sharma, Meeta
790 ## - Authors
All authors Bansal R, Baral N, Basyal B, Kantorovich V, Kulkarni K, Lee W, Sharma M
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.aace.2020.11.011">https://dx.doi.org/10.1016/j.aace.2020.11.011</a>
Public note https://dx.doi.org/10.1016/j.aace.2020.11.011
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 06/07/2021   33851019 33851019 06/07/2021 06/07/2021 Journal Article

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