Outcomes of Conductive Keratoplasty Combined with Corneal Crosslinking in Advanced Ectatic Corneal Disease. (Record no. 6396)

MARC details
000 -LEADER
fixed length control field 02919nam a22003857a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210607s20212021 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1177-5467
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.2147/OPTH.S259012 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 259012 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC8018415 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 33824576
245 ## - TITLE STATEMENT
Title Outcomes of Conductive Keratoplasty Combined with Corneal Crosslinking in Advanced Ectatic Corneal Disease.
251 ## - Source
Source Clinical Ophthalmology. 15:1317-1329, 2021.
252 ## - Abbreviated Source
Abbreviated source Clin. ophthalmol.. 15:1317-1329, 2021.
253 ## - Journal Name
Journal name Clinical ophthalmology (Auckland, N.Z.)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
266 ## - Date added to catalog
Date added to catalog 2021-06-07
520 ## - SUMMARY, ETC.
Abstract Conclusion: Conductive keratoplasty with a proprietary epi-on CXL treatment improved vision in patients with advanced ectasia This CK/epi-on CXL treatment offers the possibility of improved VA for patients with compromised vision due to ectasia. Copyright (c) 2021 Sinjab et al.
520 ## - SUMMARY, ETC.
Abstract Methods: Retrospective, exploratory cohort study. Patients with keratoconus or postsurgical ectasia and best spectacle-corrected distance VA (CDVA) <= 20/40 were included. Conductive keratoplasty was performed (ViewPoint CK System, Refractec, Inc., Bloomington, MN); followed a day later by epi-on CXL (CXLUSA/CXLO, Bethesda, MD/CXLO Encinitas, CA). Measures included uncorrected distance visual acuity (UDVA) and CDVA, as well as refractive and tomographic measures and tomographic indices.
520 ## - SUMMARY, ETC.
Abstract Purpose: To assess the effectiveness of a novel treatment for patients with advanced corneal ectasia and loss of visual acuity (VA). Conductive keratoplasty (CK) is performed to improve VA followed by epithelium-on (epi-on) corneal crosslinking (CXL) to stabilize the cornea after CK.
520 ## - SUMMARY, ETC.
Abstract Results: Data from 50 eyes of 45 patients were analyzed. Mean follow-up was 15.1 +/- 12.2 months (range: 2 to 51). Overall, UDVA and CDVA improved postoperatively. Subjective refraction and tomographic metrics did not show consistent changes, but changes in tomographic indices were associated with treatment follow-up time. At the 1-year visit, mean UDVA significantly improved over baseline (P = 0.009) by approximately 3 lines; mean CDVA improved significantly (P = 10-5) by approximately 2 lines. No eye lost lines of CDVA. Change in the Index of Surface Variance (ISV) was associated with treatment, and the D-Index trended over follow-up time.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Ophthalmology
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Rubinfeld, Roy S
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Wagner, Kirsten
790 ## - Authors
All authors Belin MW, Cummings AB, Parsons Jnr EC, Rubinfeld RS, Sinjab MM, Wagner K
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.2147/OPTH.S259012">https://dx.doi.org/10.2147/OPTH.S259012</a>
Public note https://dx.doi.org/10.2147/OPTH.S259012
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
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          MedStar Authors Catalog MedStar Authors Catalog 06/07/2021   33824576 33824576 06/07/2021 06/07/2021 Journal Article

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