MARC details
| 000 -LEADER |
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| fixed length control field |
03655nam a22005537a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
210628s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0002-8703 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.ahj.2021.04.013 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S0002-8703(21)00115-0 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
33961829 |
| 245 ## - TITLE STATEMENT |
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| Title |
Cangrelor vs. Glycoprotein IIb/IIIa Inhibitors During Percutaneous Coronary Intervention. |
| 251 ## - Source |
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| Source |
American Heart Journal. 2021 May 04 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Am Heart J. 2021 May 04 |
| 253 ## - Journal Name |
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| Journal name |
American heart journal |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2021 May 04 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
aheadofprint |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-06-28 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: To date, there are no real-world studies comparing cangrelor to glycoprotein IIb/IIIa inhibitors (GPI) during percutaneous coronary intervention (PCI). Thus, we performed this study to evaluate the safety and effectiveness of cangrelor compared to GPI during PCI. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: Balancing ischemic and bleeding risks with adjunctive antiplatelet drugs is of prime importance during PCI. Our real-world analysis shows that cangrelor is safe and effective when compared to GPI during PCI. Copyright (c) 2021. Published by Elsevier Inc. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: We identified patients who underwent PCI at our institution who received either cangrelor or GPI during PCI. Patients already on GPI or cangrelor prior to PCI or who received both cangrelor and GPI were excluded. Baseline demographics and clinical outcomes were extracted. Major bleeding is defined as a composite of major hematoma >4 cm, hematocrit drop >15, and gastrointestinal bleeding. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: A total of 2072 patients received adjunctive antiplatelet therapy during PCI (cangrelor [n=478]; GPI [n=1594]). Patients' mean age was 61+/-12 years. Most (66%) presented with acute coronary syndrome. Patients who received cangrelor were older and had a higher percentage of acute coronary syndrome and lower baseline hematocrit in comparison with patients who received GPI. Procedural success was achieved in 94% of patients, with no difference between groups. Major bleeding events (1.7% vs. 5.1%, p=0.001), any vascular complication rates, and hospital length of stay were significantly lower in the cangrelor group. In-hospital ischemic events did not differ between groups. On regression analysis, patients on cangrelor were noted to have significantly lower major bleeding events (OR 0.23; 95% CI, 0.09-0.59). |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Advanced Cardiac Catheterization Research Fellowship |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Interventional Cardiology Fellowship |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Ben-Dor, Itsik |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Bernardo, Nelson L |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Case, Brian |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Chezar-Azerrad, Chava |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Forrestal, Brian |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Garcia-Garcia, Hector M |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Hashim, Hayder |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Medranda, Giorgio |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Satler, Lowell F |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Shea, Corey |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Waksman, Ron |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Yerasi, Charan |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Zhang, Cheng |
| 790 ## - Authors |
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| All authors |
Ben-Dor I, Bernardo NL, Case BC, Chezar-Azerrad C, Forrestal BJ, Garcia-Garcia HM, Hashim H, Medranda GA, Satler LF, Shea C, Waksman R, Yerasi C, Zhang C |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.ahj.2021.04.013">https://dx.doi.org/10.1016/j.ahj.2021.04.013</a> |
| Public note |
https://dx.doi.org/10.1016/j.ahj.2021.04.013 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
