Good outcome associated with blood-brain barrier disruption and lower blood pressure after endovascular therapy. (Record no. 65)

MARC details
000 -LEADER
fixed length control field 03332nam a22004217a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 221213s20222022 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1052-3057
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.jstrokecerebrovasdis.2022.106870 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S1052-3057(22)00562-6 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 36434858
245 ## - TITLE STATEMENT
Title Good outcome associated with blood-brain barrier disruption and lower blood pressure after endovascular therapy.
251 ## - Source
Source Journal of Stroke & Cerebrovascular Diseases. 32(1):106870, 2022 Nov 23.
252 ## - Abbreviated Source
Abbreviated source J STROKE CEREBROVASC DIS. 32(1):106870, 2022 Nov 23.
253 ## - Journal Name
Journal name Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2022
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Manufacturer FY2023
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2022 Nov 23
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
266 ## - Date added to catalog
Date added to catalog 2022-12-13
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: BBB disruption on 3h post-EVT imaging and lower SBP was associated with favorable outcome. This imaging finding may guide targeted BP therapy and suggests need for a randomized control trial. Copyright Published by Elsevier Inc.
520 ## - SUMMARY, ETC.
Abstract METHODS: This is a single-center study of 1) anterior large vessel occlusion stroke patients treated with EVT from 2015 to 2021, 2) achieved mTICI grade 2b or 3. Hyperintense acute reperfusion marker (HARM), hemorrhagic transformation (HT), and midline shift at 3 h post-EVT and 24 h imaging were assessed independently by multiple raters. Binary logistic regression models were used to determine the association of post-EVT SBP with outcomes. BBB disruption was defined as HT or HARM on 3h post-EVT imaging.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVES: To evaluate the association between post-endovascular thrombectomy (EVT) blood-brain barrier (BBB) disruption on MRI or CT and average systolic blood pressure (SBP) with favorable 90-day functional outcome. Observational studies have found elevated SBP associated with worse outcomes post-EVT, while recent randomized trials found no difference in targeted BP reduction. There may be a subgroup of patients who benefit from targeted BP reduction post-EVT.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Of 103 patients, those with SBP 100-129 versus SBP 130-160 found no significant difference in favorable 90-day outcome (64% vs. 46%, OR 2.11, 95% CI 0.78-5.76, p=0.143). However, among 71 patients with BBB disruption, a significant difference in favorable outcome of 64% in SBP 100-129 vs. 39% in SBP 130-160 group (OR 5.93, 95% CI 1.50-23.45, p=0.011) was found. There was no difference in symptomatic ICH, 90-day mortality, midline shift (>=5 mm), and hemicraniectomy, between BP or BBB groups.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
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Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
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Department Neurology
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Department Neurology Residency
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Hsia, Amie W
Institution Code MWHC
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Kim, Yongwoo
Institution Code MWHC
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Mehta, Amit
Institution Code MGUH
Program Neurology Residency
Degree MD
Resident year Resident PGY 4
790 ## - Authors
All authors Ansari S, Hsia AW, Kim Y, Latour LL, Luby M, Lynch JK, Mehta A, Upadhyaya P
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106870">https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106870</a>
Public note https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106870
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 12/13/2022   36434858 36434858 12/13/2022 12/13/2022 Journal Article

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