MARC details
000 -LEADER |
fixed length control field |
03332nam a22004217a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
221213s20222022 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1052-3057 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.jstrokecerebrovasdis.2022.106870 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S1052-3057(22)00562-6 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
36434858 |
245 ## - TITLE STATEMENT |
Title |
Good outcome associated with blood-brain barrier disruption and lower blood pressure after endovascular therapy. |
251 ## - Source |
Source |
Journal of Stroke & Cerebrovascular Diseases. 32(1):106870, 2022 Nov 23. |
252 ## - Abbreviated Source |
Abbreviated source |
J STROKE CEREBROVASC DIS. 32(1):106870, 2022 Nov 23. |
253 ## - Journal Name |
Journal name |
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2023 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Nov 23 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2022-12-13 |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: BBB disruption on 3h post-EVT imaging and lower SBP was associated with favorable outcome. This imaging finding may guide targeted BP therapy and suggests need for a randomized control trial. Copyright Published by Elsevier Inc. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: This is a single-center study of 1) anterior large vessel occlusion stroke patients treated with EVT from 2015 to 2021, 2) achieved mTICI grade 2b or 3. Hyperintense acute reperfusion marker (HARM), hemorrhagic transformation (HT), and midline shift at 3 h post-EVT and 24 h imaging were assessed independently by multiple raters. Binary logistic regression models were used to determine the association of post-EVT SBP with outcomes. BBB disruption was defined as HT or HARM on 3h post-EVT imaging. |
520 ## - SUMMARY, ETC. |
Abstract |
OBJECTIVES: To evaluate the association between post-endovascular thrombectomy (EVT) blood-brain barrier (BBB) disruption on MRI or CT and average systolic blood pressure (SBP) with favorable 90-day functional outcome. Observational studies have found elevated SBP associated with worse outcomes post-EVT, while recent randomized trials found no difference in targeted BP reduction. There may be a subgroup of patients who benefit from targeted BP reduction post-EVT. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Of 103 patients, those with SBP 100-129 versus SBP 130-160 found no significant difference in favorable 90-day outcome (64% vs. 46%, OR 2.11, 95% CI 0.78-5.76, p=0.143). However, among 71 patients with BBB disruption, a significant difference in favorable outcome of 64% in SBP 100-129 vs. 39% in SBP 130-160 group (OR 5.93, 95% CI 1.50-23.45, p=0.011) was found. There was no difference in symptomatic ICH, 90-day mortality, midline shift (>=5 mm), and hemicraniectomy, between BP or BBB groups. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
MedStar Georgetown University Hospital/MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Neurology |
656 ## - INDEX TERM--OCCUPATION |
Department |
Neurology Residency |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Hsia, Amie W |
Institution Code |
MWHC |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Kim, Yongwoo |
Institution Code |
MWHC |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Mehta, Amit |
Institution Code |
MGUH |
Program |
Neurology Residency |
Degree |
MD |
Resident year |
Resident PGY 4 |
790 ## - Authors |
All authors |
Ansari S, Hsia AW, Kim Y, Latour LL, Luby M, Lynch JK, Mehta A, Upadhyaya P |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106870">https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106870</a> |
Public note |
https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106870 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |