Prognostic value of left atrial size in hypertensive African Americans undergoing stress echocardiography. (Record no. 874)

MARC details
000 -LEADER
fixed length control field 03553nam a22003617a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220221s20212021 xxu||||| |||| 00| 0 eng d
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.4330/wjc.v13.i12.733 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC8716971 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 35070115
245 ## - TITLE STATEMENT
Title Prognostic value of left atrial size in hypertensive African Americans undergoing stress echocardiography.
251 ## - Source
Source World Journal of Cardiology. 13(12):733-744, 2021 Dec 26.
252 ## - Abbreviated Source
Abbreviated source World J Cardiol. 13(12):733-744, 2021 Dec 26.
253 ## - Journal Name
Journal name World journal of cardiology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2021 Dec 26
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2022-02-21
520 ## - SUMMARY, ETC.
Abstract AIM: To investigate the prognostic value of LA size in hypertensive AA patients undergoing stress echocardiography.
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Left atrial (LA) enlargement is a marker of increased risk in the general population undergoing stress echocardiography. African American (AA) patients with hypertension are known to have less atrial remodeling than whites with hypertension. The prognostic impact of LA enlargement in AA with hypertension undergoing stress echocardiography is uncertain.
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: LA enlargement is infrequent in hypertensive AA patients when traditional reference values are used. LA enlargement is independently associated with mortality when a lower than "normal" threshold (>= 2.05 cm/m2) is used. Copyright (c)The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract METHODS: This retrospective outcomes study enrolled 583 consecutive hypertensive AA patients who underwent stress echocardiography over a 2.5-year period. Clinical characteristics including cardiovascular risk factors, stress and echocardiographic data were collected from the electronic health record of a large community hospital. Treadmill exercise and Dobutamine protocols were conducted based on standard practices. Patients were followed for all-cause mortality. The optimal cutoff value of antero-posterior LA diameter for mortality was assessed by receiver operating characteristic analysis. Cox regression was used to determine variables associated with outcome.
520 ## - SUMMARY, ETC.
Abstract RESULTS: The mean age was 57 +/- 12 years. LA dilatation was present in 9% (54) of patients (LA anteroposterior >= 2.4 cm/m2). There were 85 deaths (15%) during 4.5 +/- 1.7 years of follow-up. LA diameter indexed for body surface area had an area under the curve of 0.72 +/- 0.03 (optimal cut-point of 2.05 cm/m2). Variables independently associated with mortality included age [P = 0.004, hazard ratio (HR) 1.34 (1.10-1.64)], tobacco use [P = 0.001, HR 2.59 (1.51-4.44)], left ventricular hypertrophy [P = 0.001 , HR 2.14 (1.35-3.39)], Dobutamine stress [P = 0.003, HR 2.12 (1.29-3.47)], heart failure history [P = 0.031, HR 1.76 (1.05-2.94)], LA diameter >= 2.05 cm/m2 [P = 0.027, HR 1.73 (1.06-2.82)], and an abnormal stress echocardiogram [P = 0.033, HR 1.67 (1.04-2.68)]. LA diameter as a continuous variable was also independently associated with mortality but LA size >= 2.40 cm/m2 was not.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Thomaides, Athanasios
790 ## - Authors
All authors Feigenbaum H, Habhab MN, Hornsby K, Khemka A, Sawada SG, Sutter DA, Thomaides A
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.4330/wjc.v13.i12.733">https://dx.doi.org/10.4330/wjc.v13.i12.733</a>
Public note https://dx.doi.org/10.4330/wjc.v13.i12.733
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
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          MedStar Authors Catalog MedStar Authors Catalog 02/21/2022   35070115 35070115 02/21/2022 02/21/2022 Journal Article

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