MedStar Authors catalog › Details for: Obstetric complications, neonatal morbidity, and indications for cesarean delivery by maternal age.
Obstetric complications, neonatal morbidity, and indications for cesarean delivery by maternal age. Journal: Obstetrics and gynecology.ISSN: 0029-7844.UI/PMID: 24201681.Subject(s): *Birth Weight | Cephalopelvic Disproportion/su [Surgery] | *Cesarean Section/sn [Statistics & Numerical Data] | Cicatrix/pa [Pathology] | Cicatrix/su [Surgery] | Dystocia/su [Surgery] | Female | Fetal Distress/su [Surgery] | Humans | Hypertension, Pregnancy-Induced/ep [Epidemiology] | Infant, Newborn | Intensive Care, Neonatal/sn [Statistics & Numerical Data] | *Maternal Age | Perinatal Mortality | Pregnancy | *Pregnancy Complications/ep [Epidemiology] | Retrospective Studies | Surgical Procedures, Elective/sn [Statistics & Numerical Data] | United States/ep [Epidemiology] | *Uterus/pa [Pathology]Institution(s): MedStar Health Research Institute | MedStar Washington Hospital CenterDepartment(s): Obstetrics and Gynecology, Maternal-Fetal MedicineActivity type: Journal Article.Medline article type(s): Journal Article | Research Support, N.I.H., ExtramuralOnline resources: Click here to access online Digital Object Identifier: http://dx.doi.org/10.1097/AOG.0000000000000017 (Click here) Abbreviated citation: Obstet Gynecol. 122(6):1184-95, 2013 Dec.Local Holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006.Abstract: OBJECTIVE: To delineate adverse obstetric and neonatal outcomes as well as indications for cesarean delivery by maternal age in a contemporaneous large national cohort.Abstract: METHODS: This was a retrospective analysis of electronic medical records from 12 centers and 203,517 (30,673 women aged 35 years or older) women with singleton gestations stratified by maternal age. Logistic regression was performed to investigate maternal and neonatal outcomes for each maternal age strata (referent group, age 25.0-29.9 years), adjusting for race, parity, body mass index, insurance, pre-existing medical conditions, substance and tobacco use, and site. Documented indications for cesarean delivery were analyzed.Abstract: RESULTS: Neonates born to women aged 25.0-29.9 years had the lowest risk of birth weight less than 2,500 g (7.2%; P<.001), admission to neonatal intensive care unit (11.5%; P<.001), and perinatal mortality (0.7%; P<.001). Hypertensive disorders of pregnancy were higher in women aged 35 years or older (cumulative rate 8.5% compared with 7.8%; 25.0-29.9 years; P<.001). Previous uterine scar was the leading indication for cesarean delivery in women aged 25.0 years or older (36.9%; P<.001). For younger women, failure to progress or cephalopelvic disproportion (37.0% for those younger than age 20.0 years and 31.1% for those aged 20.0-24.9-years; P<.001) and nonreassuring fetal heart tracing (28.7% for those younger than 20.0 years and 21.2% for those aged 20.0-24.9-years; P<.001) predominated as indications. Truly elective cesarean delivery rate was 20.2% for women aged 45.0 years or older (adjusted odds ratio 1.85 [99% confidence interval 1.03-3.32] compared with the referent age group of 25.0-29.9 years).Abstract: CONCLUSIONS: Maternal and obstetric complications differed by maternal age, as did rates of elective cesarean delivery. Women aged 25.0-29.9 years had the lowest rate of serious neonatal morbidity.Abstract: LEVEL OF EVIDENCE: : II.