Silent and formidable foe: neuroendocrine tumours of the gallbladder.

MedStar author(s):
Citation: BMJ Case Reports. 13(12), 2020 Dec 22.PMID: 33370977Institution: MedStar Medical GroupDepartment: MedStar Health Baltimore ResidentsForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Carcinoma, Neuroendocrine/di [Diagnosis] | *Cholecystitis, Acute/et [Etiology] | *Gallbladder Neoplasms/di [Diagnosis] | *Gallbladder/pa [Pathology] | *Peritoneal Neoplasms/di [Diagnosis] | Aged, 80 and over | Carcinoma, Neuroendocrine/sc [Secondary] | Carcinoma, Neuroendocrine/th [Therapy] | Cholecystectomy, Laparoscopic | Cholecystitis, Acute/su [Surgery] | Fatal Outcome | Female | Gallbladder Neoplasms/co [Complications] | Gallbladder Neoplasms/pa [Pathology] | Gallbladder Neoplasms/th [Therapy] | Gallbladder/dg [Diagnostic Imaging] | Gallbladder/su [Surgery] | Hospice Care | Humans | Missed Diagnosis | Neoplasm Staging | Peritoneal Neoplasms/sc [Secondary] | Peritoneal Neoplasms/th [Therapy] | Tomography, X-Ray ComputedYear: 2020ISSN:
  • 1757-790X
Name of journal: BMJ case reportsAbstract: Neuroendocrine neoplasms of the gallbladder occur infrequently, with the diagnosis being incidental in most cases. We present a case of an 81-year-old African American woman who initially presented with acute suppurative cholecystitis, found on pathology to have a moderately differentiated infiltrating adenocarcinoma. A partial hepatic resection with periportal lymph node dissection was planned which was subsequently aborted intraoperatively due to the presence of diffuse carcinomatosis. Pathology of the cancerous lesions revealed neuroendocrine carcinoma. Gallbladder neuroendocrine tumours demonstrate no specific clinical features. Given its often late presentation, neuroendocrine tumours of the gallbladder pose a therapeutic and prognostic challenge. Copyright (c) BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.All authors: McCarron E, Randhawa DS, Shoucair SOriginally published: BMJ Case Reports. 13(12), 2020 Dec 22.Fiscal year: FY2021Digital Object Identifier: ORCID: Date added to catalog: 2021-02-17
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Journal Article MedStar Authors Catalog Article 33370977 Available 33370977

Neuroendocrine neoplasms of the gallbladder occur infrequently, with the diagnosis being incidental in most cases. We present a case of an 81-year-old African American woman who initially presented with acute suppurative cholecystitis, found on pathology to have a moderately differentiated infiltrating adenocarcinoma. A partial hepatic resection with periportal lymph node dissection was planned which was subsequently aborted intraoperatively due to the presence of diffuse carcinomatosis. Pathology of the cancerous lesions revealed neuroendocrine carcinoma. Gallbladder neuroendocrine tumours demonstrate no specific clinical features. Given its often late presentation, neuroendocrine tumours of the gallbladder pose a therapeutic and prognostic challenge. Copyright (c) BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

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