Anagen Effluvium in Association With Extracorporeal Membrane Oxygenation.

MedStar author(s):
Citation: Pediatric Dermatology. 34(4):e201-e202, 2017 Jul.PMID: 28612487Institution: MedStar Washington Hospital CenterDepartment: DermatologyForm of publication: Journal ArticleMedline article type(s): Case ReportsSubject headings: *Alopecia/et [Etiology] | *Extracorporeal Membrane Oxygenation/ae [Adverse Effects] | *Reperfusion Injury/co [Complications] | Child, Preschool | Hair Follicle/pa [Pathology] | Humans | Hypotension/co [Complications] | Hypoxia/co [Complications] | MaleYear: 2017ISSN:
  • 0736-8046
Name of journal: Pediatric dermatologyAbstract: Anagen effluvium (AE) is a type of alopecia with hair loss during the growth phase of a hair follicle and is most often associated with cytotoxic chemotherapy. This report describes a case of AE in a critically ill 2-year-old boy who developed cardiorespiratory failure requiring extracorporeal membranous oxygenation. We postulate that the combination of hypotension and hypoxia with subsequent reperfusion triggered an apoptotic cascade in the hair matrix, resulting in AE.Copyright � 2017 Wiley Periodicals, Inc.All authors: Cheng K, Cotter L, Kirkorian AYFiscal year: FY2017Digital Object Identifier: ORCID: Date added to catalog: 2017-06-16
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Journal Article MedStar Authors Catalog Article 28612487 Available 28612487

Anagen effluvium (AE) is a type of alopecia with hair loss during the growth phase of a hair follicle and is most often associated with cytotoxic chemotherapy. This report describes a case of AE in a critically ill 2-year-old boy who developed cardiorespiratory failure requiring extracorporeal membranous oxygenation. We postulate that the combination of hypotension and hypoxia with subsequent reperfusion triggered an apoptotic cascade in the hair matrix, resulting in AE.

Copyright � 2017 Wiley Periodicals, Inc.

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