Successful maternal and fetal outcome in a kidney transplant patient with everolimus exposure throughout pregnancy: a case report.

MedStar author(s):
Citation: Transplantation Proceedings. 46(1):281-3, 2014 Jan-Feb.PMID: 24507068Institution: MedStar Washington Hospital CenterDepartment: Medicine/Nephrology | Obstetrics and Gynecology/Pediatric and AdolescentForm of publication: Journal ArticleMedline article type(s): Case Reports | Journal ArticleSubject headings: *Immunosuppressive Agents/ad [Administration & Dosage] | *Kidney Failure, Chronic/co [Complications] | *Kidney Failure, Chronic/su [Surgery] | *Kidney Transplantation | *Maternal Exposure | *Sirolimus/aa [Analogs & Derivatives] | Adult | Female | Humans | Immunosuppressive Agents/ae [Adverse Effects] | Infant, Newborn | Male | Patient Safety | Pregnancy | Pregnancy Complications | Pregnancy Outcome | Risk | Sirolimus/ad [Administration & Dosage] | Sirolimus/ae [Adverse Effects] | Treatment OutcomeLocal holdings: Available online from MWHC library: 1997 - present, Available in print through MWHC library:1999-2007ISSN:
  • 0041-1345
Name of journal: Transplantation proceedingsAbstract: Pregnancy after kidney transplantation is becoming more common as more patients of childbearing age are undergoing successful transplantation. There is limited evidence on the safety and efficacy of mammalian target of rapamycin inhibitors during pregnancy, which are considered Category C. We will review the use of this class of medications in pregnancy, which is currently contraindicated due to risk of fetal complications. We will also present the case of a successful pregnancy and renal outcome in a 33-year-old kidney transplant recipient who was administered everolimus throughout pregnancy. Copyright � 2014 Elsevier Inc. All rights reserved.All authors: Gomez-Lobo V, Margoles HR, Moore J Jr, Sherman MJ, Veis JHDigital Object Identifier: Date added to catalog: 2015-03-17
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Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article Available 24507068

Available online from MWHC library: 1997 - present, Available in print through MWHC library:1999-2007

Pregnancy after kidney transplantation is becoming more common as more patients of childbearing age are undergoing successful transplantation. There is limited evidence on the safety and efficacy of mammalian target of rapamycin inhibitors during pregnancy, which are considered Category C. We will review the use of this class of medications in pregnancy, which is currently contraindicated due to risk of fetal complications. We will also present the case of a successful pregnancy and renal outcome in a 33-year-old kidney transplant recipient who was administered everolimus throughout pregnancy. Copyright � 2014 Elsevier Inc. All rights reserved.

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