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Evidence-based management of keloids and hypertrophic scars in dermatology. [Review]

MedStar author(s):

Citation: Archives of Dermatological Research. 315(6):1487-1495, 2023 Aug.PMID: 36504113Institution: MedStar Washington Hospital CenterDepartment: Dermatology ResidencyForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Cicatrix, Hypertrophic | *Dermatology | *Keloid | Cicatrix, Hypertrophic/pa [Pathology] | Humans | Keloid/pa [Pathology] | Skin/pa [Pathology] | Wound HealingYear: 2023 ISSN:

0340-3696

Name of journal: Archives of dermatological researchAbstract: While normal, controlled wound-healing results in scars that are nearly imperceptible, hypertrophic scars (HTS) and keloids are the result of an abnormal wound-healing process that can leave unsightly, difficult-to-treat lesions. While such scars are classically associated with surgical incisions, they may also result from burns or accidental trauma to the skin. Several different measures can be taken to prevent the formation of scars or treat those that have already formed. Prevention focuses on reducing inflammation during the wound-healing process, and minimizing tension in the lesion when appropriate. Treatments range from non-invasive modalities such as pressure therapy, topicals, and symptom management, to invasive methods such as injections, lasers, and even surgery. While some treatments, such as corticosteroid injections, have been used in the treatment of HTS and keloids for decades, other newer therapies have only been described in case reports or are still in early phases of clinical trials. Because optimal scar management will not be the same for every patient, further investigation of newer agents and methods is warranted and may benefit a great number of patients. This paper will review the evidence-based management of scars, including current widely used treatment options and promising newly emerging therapies. Copyright © 2022. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.All authors: Kim EY, Hussain A, Khachemoune AOriginally published: Original year of publication: 2022Fiscal year: Fiscal year of original publication: FY2023Digital Object Identifier:

https://dx.doi.org/10.1007/s00403-022-02509-x

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Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	36504113	Available		36504113

While normal, controlled wound-healing results in scars that are nearly imperceptible, hypertrophic scars (HTS) and keloids are the result of an abnormal wound-healing process that can leave unsightly, difficult-to-treat lesions. While such scars are classically associated with surgical incisions, they may also result from burns or accidental trauma to the skin. Several different measures can be taken to prevent the formation of scars or treat those that have already formed. Prevention focuses on reducing inflammation during the wound-healing process, and minimizing tension in the lesion when appropriate. Treatments range from non-invasive modalities such as pressure therapy, topicals, and symptom management, to invasive methods such as injections, lasers, and even surgery. While some treatments, such as corticosteroid injections, have been used in the treatment of HTS and keloids for decades, other newer therapies have only been described in case reports or are still in early phases of clinical trials. Because optimal scar management will not be the same for every patient, further investigation of newer agents and methods is warranted and may benefit a great number of patients. This paper will review the evidence-based management of scars, including current widely used treatment options and promising newly emerging therapies. Copyright © 2022. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.

English