Spontaneous labor curves in women with pregnancies complicated by diabetes.

MedStar author(s):
Citation: Journal of Maternal-Fetal & Neonatal Medicine. 25(1):20-6, 2012 Jan.PMID: 21955108Institution: MedStar Health Research Institute | MedStar Washington Hospital CenterDepartment: Obstetrics and Gynecology, Maternal-Fetal MedicineForm of publication: Journal ArticleMedline article type(s): Journal Article | Research Support, N.I.H., Extramural | Research Support, N.I.H., Intramural | Research Support, Non-U.S. Gov'tSubject headings: *Labor, Obstetric/ph [Physiology] | *Pregnancy in Diabetics/pp [Physiopathology] | Adult | Birth Weight | Body Mass Index | Cohort Studies | Diabetes, Gestational/pp [Physiopathology] | Female | Fetal Macrosomia/ep [Epidemiology] | Humans | Infant, Newborn | National Institutes of Health (U.S.) | Parity | Pregnancy | Retrospective Studies | Time Factors | United StatesYear: 2012Local holdings: Available online through MWHC library: 2013 to the presentISSN:
  • 1476-4954
Name of journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal ObstetriciansAbstract: CONCLUSIONS: Labor curves of women with preDM and GDM approximate those of non-diabetics, regardless of BMI, birth weight, or parity.METHODS: A retrospective analysis was performed from 228,668 deliveries between 2002-2008 from the Consortium of Safe Labor (National Institute of Child Health and Human Development, National Institutes of Health). Patients with spontaneous onset of labor from 37 0/7-41 6/7 weeks gestation were included (71,282) and classified as nulliparous or multiparous. Pregnancies were further subdivided regarding presence of preexisting diabetes (preDM) or gestational diabetes (GDM) and normal controls. Labor curves were created matching for body mass index (BMI) and neonatal birth weight. Statistical analysis was performed on descriptive variables using (2) with significance designated as p<0.05.OBJECTIVE: To test the hypothesis that the first stage of labor will be longer in nulliparous and multiparous women with diabetes compared to non-diabetic counterparts.RESULTS: Among nulliparous patients, there were 118 women with preDM and 475 women with GDM; 25,771 patients served as normal controls. Among multiparous women, there were 311 with preDM, 1,079 with GDM and 43,528 in the control group. Although differences in dilatation rates were observed in nulliparous and multiparous women with and without diabetes, labor progression was similar between the subgroups when matched for maternal BMI and birth weight.All authors: Driggers RW, Huang CC, Landy HJ, Singh J, Timofeev JFiscal year: FY2012Digital Object Identifier: Date added to catalog: 2013-09-17
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 21955108 Available 21955108

Available online through MWHC library: 2013 to the present

CONCLUSIONS: Labor curves of women with preDM and GDM approximate those of non-diabetics, regardless of BMI, birth weight, or parity.

METHODS: A retrospective analysis was performed from 228,668 deliveries between 2002-2008 from the Consortium of Safe Labor (National Institute of Child Health and Human Development, National Institutes of Health). Patients with spontaneous onset of labor from 37 0/7-41 6/7 weeks gestation were included (71,282) and classified as nulliparous or multiparous. Pregnancies were further subdivided regarding presence of preexisting diabetes (preDM) or gestational diabetes (GDM) and normal controls. Labor curves were created matching for body mass index (BMI) and neonatal birth weight. Statistical analysis was performed on descriptive variables using (2) with significance designated as p<0.05.

OBJECTIVE: To test the hypothesis that the first stage of labor will be longer in nulliparous and multiparous women with diabetes compared to non-diabetic counterparts.

RESULTS: Among nulliparous patients, there were 118 women with preDM and 475 women with GDM; 25,771 patients served as normal controls. Among multiparous women, there were 311 with preDM, 1,079 with GDM and 43,528 in the control group. Although differences in dilatation rates were observed in nulliparous and multiparous women with and without diabetes, labor progression was similar between the subgroups when matched for maternal BMI and birth weight.

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