Citation: American Journal of Cardiology. 117(1):135-40, 2016 Jan 1..Journal: The American journal of cardiology.Published: 2016ISSN: 0002-9149.Full author list: Patel R; Lim RP; Saric M; Nayar A; Babb J; Ettel M; Axel L; Srichai MB.UI/PMID: 26552505.Subject(s): Adult | Diagnosis, Differential | *Echocardiography/mt [Methods] | Female | *Heart Neoplasms/di [Diagnosis] | Humans | *Magnetic Resonance Imaging, Cine/mt [Methods] | Male | Middle Aged | *Pericardial Effusion/di [Diagnosis] | Predictive Value of Tests | Reproducibility of Results | Retrospective StudiesInstitution(s): MedStar Washington Hospital CenterDepartment(s): MedStar Heart InstituteActivity type: Journal Article.Medline article type(s): Journal Article | Research Support, U.S. Gov't, P.H.SOnline resources: Click here to access onlineDigital Object Identifier: http://dx.doi.org/10.1016/j.amjcard.2015.10.014 (Click here)Abbreviated citation: Am J Cardiol. 117(1):135-40, 2016 Jan 1.Local Holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006.Abstract: Echocardiography is the preferred initial imaging method for assessment of cardiac masses. Cardiac magnetic resonance (CMR) imaging, with its excellent tissue characterization and wide field of view, may provide additional unique information. We evaluated the predictive value of echocardiography and CMR imaging parameters to identify tumors and malignancy and to provide histopathologic diagnosis of cardiac masses. Fifty patients who underwent CMR evaluation of a cardiac mass with subsequent histopathologic diagnosis were identified. Echocardiography was available in 44 of 50 cases (88%). Echocardiographic and CMR characteristics were evaluated for predictive value in distinguishing tumor versus nontumor and malignant versus nonmalignant lesions using histopathology as the gold standard. The Wilcoxon rank-sum test was used to compare the 2 imaging methods' ability to provide the correct histopathologic diagnosis. Parameters associated with tumor included location outside the right atrium, T2 hyperintensity, and contrast enhancement. Parameters associated with malignancy included location outside the cardiac chambers, nonmobility, pericardial effusion, myocardial invasion, and contrast enhancement. CMR identified 6 masses missed on transthoracic echocardiography (4 of which were outside the heart) and provided significantly more correct histopathologic diagnoses compared to echocardiography (77% vs 43%, p <0.0001). In conclusion, CMR offers the advantage of identifying paracardiac masses and providing crucial information on histopathology of cardiac masses. Copyright Published by Elsevier Inc.