MedStar Authors catalog › Details for: Prevalence and predictors of left atrial thrombus in patients with atrial fibrillation: is transesophageal echocardiography necessary before cardioversion?.
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Prevalence and predictors of left atrial thrombus in patients with atrial fibrillation: is transesophageal echocardiography necessary before cardioversion?.

by Malik, Rahul; Wang, Zuyue; Goldstein, Steven A; Torguson, Rebecca; Lindsay, Joseph; Waksman, Ron; Ben-Dor, Itsik.
Citation: Cardiovascular Revascularization Medicine. 16(1):12-4, 2015 Jan-Feb..Journal: Cardiovascular revascularization medicine : including molecular interventions.ISSN: 1878-0938.Full author list: Malik R; Alyeshmerni DM; Wang Z; Goldstein SA; Torguson R; Lindsay J; Waksman R; Ben-Dor I.UI/PMID: 25666720.Subject(s): Aged | Atrial Fibrillation/ep [Epidemiology] | Atrial Fibrillation/pp [Physiopathology] | *Atrial Fibrillation/th [Therapy] | *Atrial Fibrillation/us [Ultrasonography] | *Echocardiography, Transesophageal | *Electric Countershock | Female | Humans | Male | Middle Aged | Predictive Value of Tests | Prevalence | Prognosis | Reproducibility of Results | Retrospective Studies | Risk Factors | Thrombosis/ep [Epidemiology] | Thrombosis/pp [Physiopathology] | *Thrombosis/us [Ultrasonography]Institution(s): MedStar Heart & Vascular InstituteActivity type: Journal Article.Medline article type(s): Journal ArticleDigital Object Identifier: http://dx.doi.org/10.1016/j.carrev.2014.12.009 (Click here) Abbreviated citation: Cardiovasc Revasc Med. 16(1):12-4, 2015 Jan-Feb.Local Holdings: Available in print through MWHC library: 2002 - present.Abstract: BACKGROUND: Systemic embolization threatens patients with atrial fibrillation (AF). The risk is enhanced at the time of cardioversion. Transesophageal echocardiography (TEE) prior to cardioversion to screen for left atrial thrombus (LAT), a marker of high risk for embolization, is recommended for many patients with AF; OBJECTIVE: To determine clinical and echocardiographic factors associated with LAT formation in AF; METHODS: Data from 600 consecutive patients with AF undergoing TEE prior to cardioversion for the detection of LAT were analyzed. Clinical, laboratory, and echocardiographic parameters were abstracted from the clinical record; RESULTS: TEE identified LAT in 70 (11.6%) and dense (LA) spontaneous echo contrast (SEC) in 156 (26%). Baseline characteristics and echocardiographic parameters of patients with or without LAT are compared. A prior myocardial infarction, 21 (29.4 %) vs. 31 (5.8), (p < 0.001); hypertension, 60 (85.7%) vs. 386 (72.8), (p 0.02); CHADS(2) > 2, 56 (80%) vs. 308 (58.1%), (p < 0.001) prevalence was higher in patients with LAT. Patients with LAT had lower ejection fraction 38.2 +/- 15.6 vs. 46.2 +/- 14.5, (p < 0.001); higher LA diameter 4.98 +/- 0.7 vs. 4.52 +/- 0.7, (p <0.001); dense LA SEC 44 (62.8) vs. 112 (21.1), (p < 0.001); and low LA appendage emptying velocity 21.7 +/- 12.9 vs. 37.5 +/- 19.4, (p < 0.001). Multivariate analysis was done, and it revealed that low LA emptying velocity had the strongest independent association with LAT (HR 0.89 [CI 0.83-0.96], p value <0.001; CONCLUSION: LAT is not an uncommon finding of AF patients prior to cardioversion. The current practice of TEE examination may be justified since neither clinical nor routine 2D echo examinations reliably identify LAT.Copyright © 2014. Published by Elsevier Inc.

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