Methicillin-resistant Staphylococcus aureus pneumonia in adults. [Review]

MedStar author(s):
Citation: Expert Review of Respiratory Medicine. 8(5):641-51, 2014 Oct.PMID: 25030040Institution: MedStar Washington Hospital CenterDepartment: Medicine/Pulmonary-Critical CareForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Community-Acquired Infections/di [Diagnosis] | *Methicillin-Resistant Staphylococcus aureus | *Pneumonia, Bacterial/di [Diagnosis] | *Staphylococcal Infections/di [Diagnosis] | Anti-Bacterial Agents/tu [Therapeutic Use] | Community-Acquired Infections/dt [Drug Therapy] | Humans | Pneumonia, Bacterial/dt [Drug Therapy] | Staphylococcal Infections/dt [Drug Therapy] | Treatment OutcomeYear: 2014ISSN:
  • 1747-6348
Name of journal: Expert review of respiratory medicineAbstract: Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the leading etiologies of nosocomial pneumonia as a result of an increase in staphylococcal infections caused by methicillin-resistant strains paired with extended ventilatory support of critically, and often, chronically ill patients. The prevalence of community-acquired MRSA pneumonia, which historically affects younger patients and is often preceded by an influenza-like illness, is also increasing. A high index of suspicion and early initiation of appropriate antibiotics are key factors for the successful treatment of this disease. Even with early diagnosis and appropriate treatment, MRSA pneumonia still carries an unacceptably high mortality rate. This article will review historical differences between hospital-acquired and community-acquired MRSA pneumonia, as well as, clinical features of, diagnosis and treatment of MRSA pneumonia.All authors: Colice G, Woods CFiscal year: FY2015Digital Object Identifier: Date added to catalog: 2016-01-13
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Journal Article MedStar Authors Catalog Article 25030040 Available 25030040

Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the leading etiologies of nosocomial pneumonia as a result of an increase in staphylococcal infections caused by methicillin-resistant strains paired with extended ventilatory support of critically, and often, chronically ill patients. The prevalence of community-acquired MRSA pneumonia, which historically affects younger patients and is often preceded by an influenza-like illness, is also increasing. A high index of suspicion and early initiation of appropriate antibiotics are key factors for the successful treatment of this disease. Even with early diagnosis and appropriate treatment, MRSA pneumonia still carries an unacceptably high mortality rate. This article will review historical differences between hospital-acquired and community-acquired MRSA pneumonia, as well as, clinical features of, diagnosis and treatment of MRSA pneumonia.

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