Normal view MARC view ISBD view

Mesenchymal Stem Cell-Bearing Sutures for Tendon Repair and Healing in the Foot and Ankle. [Review]

MedStar author(s):

Citation: Foot & Ankle Clinics. 21(4):885-890, 2016 DecPMID: 27871421Institution: MedStar Union Memorial HospitalDepartment: Orthopaedic SurgeryForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Foot/su [Surgery] | *Mesenchymal Stem Cell Transplantation/mt [Methods] | *Mesenchymal Stromal Cells/ph [Physiology] | *Sutures | *Tendon Injuries/su [Surgery] | *Wound Healing/ph [Physiology] | Ankle/pp [Physiopathology] | Ankle/su [Surgery] | HumansYear: 2016 ISSN:

1083-7515

Name of journal: Foot and ankle clinicsAbstract: Copyright © 2016 Elsevier Inc. All rights reserved.Improving the quality and strength of soft tissue repairs remains an important area of orthopedic research and innovation. The need for immobilization and early motion is an important balance essential for the successful treatment of tendon repair and reconstruction. Mesenchymal stem cell (MSC)-bearing sutures represent an emerging biological augmentation to traditional suture repair. Two previous large studies using stem cell sutures in rat Achilles tendon models have demonstrated early increased biomechanical strength and significantly increased ultimate failure strength. The MSCs seem to remain locally at the repair site and enhance the histologic repair quality of the tendon collagen.All authors: Schon LC, Tan EWFiscal year: FY2017Digital Object Identifier:

https://dx.doi.org/10.1016/j.fcl.2016.07.015

Date added to catalog: 2017-05-08

Holdings ( 1 )
Title notes ( 3 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	27871421	Available		27871421

Improving the quality and strength of soft tissue repairs remains an important area of orthopedic research and innovation. The need for immobilization and early motion is an important balance essential for the successful treatment of tendon repair and reconstruction. Mesenchymal stem cell (MSC)-bearing sutures represent an emerging biological augmentation to traditional suture repair. Two previous large studies using stem cell sutures in rat Achilles tendon models have demonstrated early increased biomechanical strength and significantly increased ultimate failure strength. The MSCs seem to remain locally at the repair site and enhance the histologic repair quality of the tendon collagen.

English