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Prevalence of Peripheral Arterial Disease in Patients With Diabetic Charcot Neuroarthropathy.

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Citation: Journal of Foot & Ankle Surgery. 55(4):727-31, 2016 Jul-AugPMID: 27020760Institution: MedStar Washington Hospital CenterDepartment: Surgery/Podiatric SurgeryForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Arthropathy, Neurogenic/co [Complications] | *Diabetic Foot/co [Complications] | *Peripheral Arterial Disease/co [Complications] | Aged | Ankle Brachial Index | Arthropathy, Neurogenic/et [Etiology] | Case-Control Studies | Creatinine/bl [Blood] | Endovascular Procedures/sn [Statistics & Numerical Data] | Female | Humans | Ischemia/co [Complications] | Lower Extremity/bs [Blood Supply] | Male | Middle Aged | Peripheral Arterial Disease/di [Diagnosis] | Prevalence | Pulse | Retrospective StudiesYear: 2016 Local holdings: Available online through MWHC library: 2003 - present, Available in print through MWHC library:1999-2007ISSN:

1067-2516

Name of journal: The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle SurgeonsAbstract: Charcot neuroarthropathy (CN) is a serious complication of diabetes mellitus (DM) that can lead to pedal ulceration, infection, hospitalization, and amputation. Peripheral arterial disease (PAD) is also found in patients with diabetic foot disease; however, its prevalence in patients with CN has not been extensively evaluated. The aim of the present study was to evaluate the prevalence of PAD in a group of patients with CN (with and without ulceration) and compare this to a group of patients with diabetic foot ulceration (DFU) and no CN. We compared the lower extremity noninvasive arterial testing results of 85 patients with DM and CN with those from a group of 126 patients with DFU and no CN. No statistically significant differences were found in age, gender, type of DM (1 versus 2), insulin use, duration of DM, or history of dialysis between our study and control groups. The prevalence of PAD in the patients with CN was 40%. Compared with patients with DFUs, the patients with CN were less likely to have PAD (odds ratio 0.48, 95% confidence interval 0.28 to 0.85; p = .0111), ischemia (odds ratio 0.33, 95% confidence interval 0.16 to 0.69; p = .0033), or the need for revascularization (odds ratio 0.27, 95% confidence interval 0.10 to 0.73; p = .0097). Critical limb ischemia (great toe pressure <30 mm Hg) was 82% less likely in patients with CN than in patients with DFU. PAD in patients with CN is not uncommon; however, ischemia and the need for revascularization were significantly less likely than in patients with DFU without CN. Copyright � 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.All authors: Raspovic KM, Suder NC, Wukich DKFiscal year: FY2017Digital Object Identifier:

https://dx.doi.org/10.1053/j.jfas.2016.01.051

Date added to catalog: 2017-05-24

Holdings ( 1 )
Title notes ( 4 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	27020760	Available		27020760

Available online through MWHC library: 2003 - present, Available in print through MWHC library:1999-2007

Charcot neuroarthropathy (CN) is a serious complication of diabetes mellitus (DM) that can lead to pedal ulceration, infection, hospitalization, and amputation. Peripheral arterial disease (PAD) is also found in patients with diabetic foot disease; however, its prevalence in patients with CN has not been extensively evaluated. The aim of the present study was to evaluate the prevalence of PAD in a group of patients with CN (with and without ulceration) and compare this to a group of patients with diabetic foot ulceration (DFU) and no CN. We compared the lower extremity noninvasive arterial testing results of 85 patients with DM and CN with those from a group of 126 patients with DFU and no CN. No statistically significant differences were found in age, gender, type of DM (1 versus 2), insulin use, duration of DM, or history of dialysis between our study and control groups. The prevalence of PAD in the patients with CN was 40%. Compared with patients with DFUs, the patients with CN were less likely to have PAD (odds ratio 0.48, 95% confidence interval 0.28 to 0.85; p = .0111), ischemia (odds ratio 0.33, 95% confidence interval 0.16 to 0.69; p = .0033), or the need for revascularization (odds ratio 0.27, 95% confidence interval 0.10 to 0.73; p = .0097). Critical limb ischemia (great toe pressure <30 mm Hg) was 82% less likely in patients with CN than in patients with DFU. PAD in patients with CN is not uncommon; however, ischemia and the need for revascularization were significantly less likely than in patients with DFU without CN.

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