Clinical and Patient-Reported Outcomes of One-Sided Anterior Urethroplasty for Long-Segment or Panurethral Strictures.

MedStar author(s):
Citation: Urology. 111:208-213, 2018 Jan.PMID: 28864340Institution: MedStar Washington Hospital CenterDepartment: UrologyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Patient Reported Outcome Measures | *Urethra/su [Surgery] | *Urethral Stricture/su [Surgery] | Adult | Aged | Aged, 80 and over | Humans | Male | Middle Aged | Mouth Mucosa/tr [Transplantation] | Retrospective Studies | Sexual Behavior/ph [Physiology] | Treatment Outcome | Urethral Stricture/pa [Pathology] | Urination | Urologic Surgical Procedures, Male/mt [Methods] | Young AdultYear: 2018Local holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007ISSN:
  • 0090-4295
Name of journal: UrologyAbstract: CONCLUSIONS: Durable patency in most patients is demonstrated in this study. Patient-reported outcome measures indicate an improvement in urinary function and moderate effect on sexual function. Transient penile chordee was evident in 25% of patients. Copyright (c) 2017. Published by Elsevier Inc.METHODS: Patients from four institutions after single-stage repairs for long-segment urethral strictures (> 8 cm) from January 2002 to April 2016 were reviewed. Technique described by Kulkarni et al was used in all cases. Clinical outcomes included uroflowmetry (Qmax), post-void residuals (PVR). PROMs included IPSS survey, SHIM, Male Sexual Health Questionnaire (MSHQ-EjS) and Global Response Assessment questionnaire (GRA) to measure voiding, sexual, ejaculatory symptoms and overall improvement respectively.OBJECTIVES: To evaluate clinical and patient-reported urinary and sexual outcomes after a long-segment stricture repair using the one-sided urethral dissection, penile invagination and dorsal BMG onlay technique described by Kulkarni.RESULTS: Seventy-three patients with a minimum of 12-months follow-up were included. The mean age and stricture length were 56(21-80) years and 13.6(8-21) cm respectively. At a mean follow-up of 44(12-162) months, 9/73(12%) strictures recurred. The mean baseline IPSS score of 23(7-24) decreased to 10(1-17) on follow-up (p <0.001). 8/42 patients (21.4%) reported an increase and 6/42 patients (14.3%) decrease in SHIM following urethroplasty. Ejaculatory function on MSHQ-EjS improved after urethroplasty from 8 pre-operatively to 11 post-operatively (p<0.004). All patients reported improvement after urethroplasty on GRA questionnaire. Post-void dribbling and chordee occurred in 45% and 25% of patients respectively.All authors: Angulo JC, Blakely S, Daugherty M, Martins F, Nikolavsky D, Spencer J, Venkatesan KFiscal year: FY2018Digital Object Identifier: Date added to catalog: 2017-09-18
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Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 28864340 Available 28864340

Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007

CONCLUSIONS: Durable patency in most patients is demonstrated in this study. Patient-reported outcome measures indicate an improvement in urinary function and moderate effect on sexual function. Transient penile chordee was evident in 25% of patients. Copyright (c) 2017. Published by Elsevier Inc.

METHODS: Patients from four institutions after single-stage repairs for long-segment urethral strictures (> 8 cm) from January 2002 to April 2016 were reviewed. Technique described by Kulkarni et al was used in all cases. Clinical outcomes included uroflowmetry (Qmax), post-void residuals (PVR). PROMs included IPSS survey, SHIM, Male Sexual Health Questionnaire (MSHQ-EjS) and Global Response Assessment questionnaire (GRA) to measure voiding, sexual, ejaculatory symptoms and overall improvement respectively.

OBJECTIVES: To evaluate clinical and patient-reported urinary and sexual outcomes after a long-segment stricture repair using the one-sided urethral dissection, penile invagination and dorsal BMG onlay technique described by Kulkarni.

RESULTS: Seventy-three patients with a minimum of 12-months follow-up were included. The mean age and stricture length were 56(21-80) years and 13.6(8-21) cm respectively. At a mean follow-up of 44(12-162) months, 9/73(12%) strictures recurred. The mean baseline IPSS score of 23(7-24) decreased to 10(1-17) on follow-up (p <0.001). 8/42 patients (21.4%) reported an increase and 6/42 patients (14.3%) decrease in SHIM following urethroplasty. Ejaculatory function on MSHQ-EjS improved after urethroplasty from 8 pre-operatively to 11 post-operatively (p<0.004). All patients reported improvement after urethroplasty on GRA questionnaire. Post-void dribbling and chordee occurred in 45% and 25% of patients respectively.

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