MedStar Authors catalog › Details for: Aortic Regurgitation in Patients Undergoing Transcatheter Aortic Valve Replacement With the Self-Expanding CoreValve Versus the Balloon-Expandable SAPIEN XT Valve.
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Aortic Regurgitation in Patients Undergoing Transcatheter Aortic Valve Replacement With the Self-Expanding CoreValve Versus the Balloon-Expandable SAPIEN XT Valve.

by Kiramijyan, Starkis; Magalhaes, Marco A; Koifman, Edward; Didier, Romain; Escarcega, Ricardo O; Baker, Nevin C; Negi, Smita I; Minha, Sa'ar; Torguson, Rebecca; Jiaxiang, Gai; Asch, Federico M; Wang, Zuyue; Okubagzi, Petros; Gaglia, Michael AJ; Ben-Dor, Itsik; Satler, Lowell F; Pichard, Augusto D; Waksman, Ron.
Citation: American Journal of Cardiology. 117(9):1502-10, 2016 May 1..Journal: The American journal of cardiology.Published: 2016ISSN: 0002-9149.Full author list: Kiramijyan S; Magalhaes MA; Koifman E; Didier R; Escarcega RO; Baker NC; Negi SI; Minha S; Torguson R; Jiaxiang G; Asch FM; Wang Z; Okubagzi P; Gaglia MA Jr; Ben-Dor I; Satler LF; Pichard AD; Waksman R.UI/PMID: 26996768.Subject(s): Aged | Aged, 80 and over | *Aortic Valve Insufficiency/th [Therapy] | Female | *Heart Valve Prosthesis/ae [Adverse Effects] | Hospitalization | Humans | Incidence | Logistic Models | Male | Prosthesis Design | Retrospective Studies | Severity of Illness Index | *Transcatheter Aortic Valve Replacement/ae [Adverse Effects] | Treatment OutcomeInstitution(s): MedStar Heart & Vascular Institute | MedStar Health Research InstituteActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: http://dx.doi.org/10.1016/j.amjcard.2016.02.021 (Click here) Abbreviated citation: Am J Cardiol. 117(9):1502-10, 2016 May 1.Local Holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006.Abstract: The incidence of aortic regurgitation (AR) after transcatheter aortic valve replacement (TAVR) in a self-expanding and a balloon-expandable system is controversial. This study aimed to examine the incidence and severity of post-TAVR AR with the CoreValve (CV) versus the Edwards XT Valve (XT). Baseline, procedural, and postprocedural inhospital outcomes were compared. The primary end point was the incidence of post-TAVR AR of any severity, assessed with a transthoracic echocardiogram, in the CV versus XT groups. A multivariate logistic regression analysis was completed to evaluate for correlates of the primary end point. The secondary end points included the change in severity of AR at 30-day and 1-year follow-up. A total of 223 consecutive patients (53% men, mean age 82 years) who had transfemoral TAVR with either a CV (n = 119) or XT (n = 104) were evaluated. The rates of post-TAVR AR in the groups were similar, and there was no evidence of more-than-moderate AR in either group. There were significant differences in the rates of intraprocedural balloon postdilation with the CV (17.1%) versus XT valve (5.8%; p = 0.009) and in the rates of intraprocedural implantation of a second valve-in-valve prosthesis with the CV (9.9%) versus XT valve (2.2%; p = 0.036). There were no significant differences in inhospital safety outcomes between the 2 groups. In conclusion, the incidence of post-TAVR AR is similar between the CV and the XT valve when performed by experienced operators using optimal intraprocedural strategies, as deemed appropriate, to mitigate the severity of AR.Copyright © 2016 Elsevier Inc. All rights reserved.

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