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Evaluation and Management of Congenital Bleeding Disorders. [Review]

MedStar author(s):

Citation: Hematology - Oncology Clinics of North America. 31(6):1105-1122, 2017 DecPMID: 29078926Institution: MedStar Washington Hospital CenterDepartment: Emergency MedicineForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Blood Coagulation Disorders, Inherited/di [Diagnosis] | *Blood Coagulation Disorders, Inherited/dt [Drug Therapy] | *Blood Coagulation Factors/tu [Therapeutic Use] | *Emergency Medical Services/mt [Methods] | *Factor VIII/tu [Therapeutic Use] | *Fibrinogen/tu [Therapeutic Use] | Humans | Wounds and Injuries/di [Diagnosis] | Wounds and Injuries/th [Therapy]Year: 2017 Local holdings: Available online from MWHC library: 1996 - presentISSN:

0889-8588

Name of journal: Hematology/oncology clinics of North AmericaAbstract: Copyright (c) 2017 Elsevier Inc. All rights reserved.Patients presenting to the emergency department with acute bleeding and a history of clotting or platelet disorder present a unique challenge to the emergency physician. The severity of bleeding presentation is based on mechanism as well as factor levels: patients with factor levels greater than 5% can respond to most minor hemostatic challenges, whereas those with factor levels less than 1% bleed with minor trauma or even spontaneously. Treatment should be initiated in consultation with the patient's hematologist using medications and specific factor replacement, except in rare, life-threatening, resource-poor situations, when cryoprecipitate or activated prothrombin complex may be considerations.All authors: Bhat R, Cabey WFiscal year: FY2018Digital Object Identifier:

https://dx.doi.org/10.1016/j.hoc.2017.08.011

Date added to catalog: 2017-11-10

Holdings ( 1 )
Title notes ( 4 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	29078926	Available		29078926

Available online from MWHC library: 1996 - present

Patients presenting to the emergency department with acute bleeding and a history of clotting or platelet disorder present a unique challenge to the emergency physician. The severity of bleeding presentation is based on mechanism as well as factor levels: patients with factor levels greater than 5% can respond to most minor hemostatic challenges, whereas those with factor levels less than 1% bleed with minor trauma or even spontaneously. Treatment should be initiated in consultation with the patient's hematologist using medications and specific factor replacement, except in rare, life-threatening, resource-poor situations, when cryoprecipitate or activated prothrombin complex may be considerations.

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