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U.S. drug shortages for medications used in adult critical care (2001-2016).

MedStar author(s):

Citation: Journal of Critical Care. 41:283-288, 2017 Jun 09PMID: 28622641Institution: MedStar Union Memorial Hospital | MedStar Washington Hospital CenterDepartment: Emergency Medicine | Medicine/Pulmonary Critical Care | SurgeryForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Critical Care/ut [Utilization] | *Emergency Service, Hospital/sn [Statistics & Numerical Data] | *Pharmacy Service, Hospital/sn [Statistics & Numerical Data] | *Prescription Drugs/sd [Supply & Distribution] | Drug Substitution | Humans | UtahYear: 2017 Local holdings: Available online through MWHC library: 2012 - presentISSN:

0883-9441

Name of journal: Journal of Critical CareAbstract: CONCLUSIONS: Although the number of new shortages peaked in 2011 and is now declining, there remain a substantial number of active shortages impacting critical care drugs.Copyright 2017. Published by Elsevier Inc.MATERIALS AND METHODS: Shortages within the scope of critical care were identified using data from the University of Utah Drug Information Services. Shortage characteristics were described using standard descriptive statistics and regression analysis.PURPOSE: We describe trends in U.S. shortages impacting critical care drugs from 2001 to 2016.RESULTS: Of 1969 shortages reported, 1004 (51%) were for drugs used in critical care. New shortages fell from 2001 to 2004, then increased, peaking in 2011 (116). For critical care shortages, 247 (24.6%) involved drugs used for high acuity conditions. The majority of drugs on shortage were parenteral, (720; 71.7%) and 393 (39.1%) were single source drugs. Alternatives were available for 887 (88.3%) drugs, although 250 (24.9%) alternatives were impacted by shortages. Infectious disease drugs were the most common drugs on shortage, with 200 (19.9%) shortages, with a median duration of 7.7months (IQR=2.8-17.3). By the end of the study, 896 (89.2%) shortages were resolved and 108 (10.8%) remained active. The median duration for active shortages was 13.6months (IQR=5.8-58.4) while the duration for resolved shortages was 7.2months (IQR=2.8-17.3).All authors: Fox ER, Goyal M, Hawley KL, Mazer-Amirshahi M, Pines JM, Umar SA, Zocchi MFiscal year: FY2017Digital Object Identifier:

https://dx.doi.org/10.1016/j.jcrc.2017.06.005

Date added to catalog: 2017-06-22

Holdings ( 1 )
Title notes ( 7 )

Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	28622641	Available		28622641

Available online through MWHC library: 2012 - present

CONCLUSIONS: Although the number of new shortages peaked in 2011 and is now declining, there remain a substantial number of active shortages impacting critical care drugs.

MATERIALS AND METHODS: Shortages within the scope of critical care were identified using data from the University of Utah Drug Information Services. Shortage characteristics were described using standard descriptive statistics and regression analysis.

PURPOSE: We describe trends in U.S. shortages impacting critical care drugs from 2001 to 2016.

RESULTS: Of 1969 shortages reported, 1004 (51%) were for drugs used in critical care. New shortages fell from 2001 to 2004, then increased, peaking in 2011 (116). For critical care shortages, 247 (24.6%) involved drugs used for high acuity conditions. The majority of drugs on shortage were parenteral, (720; 71.7%) and 393 (39.1%) were single source drugs. Alternatives were available for 887 (88.3%) drugs, although 250 (24.9%) alternatives were impacted by shortages. Infectious disease drugs were the most common drugs on shortage, with 200 (19.9%) shortages, with a median duration of 7.7months (IQR=2.8-17.3). By the end of the study, 896 (89.2%) shortages were resolved and 108 (10.8%) remained active. The median duration for active shortages was 13.6months (IQR=5.8-58.4) while the duration for resolved shortages was 7.2months (IQR=2.8-17.3).

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