Citation: American Journal of Cardiology. 119(10):1507-1511, 2017 May 15.Journal: The American journal of cardiology.Published: 2017ISSN: 0002-9149.Full author list: Steinvil A; Garcia-Garcia HM; Rogers T; Koifman E; Buchanan K; Alraies MC; Torguson R; Pichard AD; Satler LF; Ben-Dor I; Waksman R.UI/PMID: 28341354.Institution(s): MedStar Heart & Vascular InstituteActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access onlineDigital Object Identifier: https://dx.doi.org/10.1016/j.amjcard.2017.02.032 (Click here)Abbreviated citation: Am J Cardiol. 119(10):1507-1511, 2017 May 15.Local Holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006MH - *Acute Kidney Injury/di [Diagnosis]MH - Acute Kidney Injury/ep [Epidemiology]MH - Acute Kidney Injury/et [Etiology]MH - AgedMH - *Catheterization, Peripheral/ae [Adverse Effects]MH - District of Columbia/ep [Epidemiology]MH - FemaleMH - Femoral ArteryMH - Follow-Up StudiesMH - HumansMH - IncidenceMH - MaleMH - Middle AgedMH - Myocardial Infarction/di [Diagnosis]MH - *Myocardial Infarction/su [Surgery]MH - Percutaneous Coronary Intervention/ae [Adverse Effects]MH - *Percutaneous Coronary Intervention/mt [Methods]MH - *Postoperative ComplicationsMH - *Propensity ScoreMH - Radial ArteryMH - RegistriesMH - Retrospective StudiesMH - Risk Assessment/mt [Methods]MH - Risk FactorsMH - Time Factors.Abstract: Transradial percutaneous coronary intervention (TR-PCI) may be associated with reduced rates of acute kidney injury (AKI). There is limited data from real-world registries about AKI rates stratified by PCI access. Our aim was to evaluate AKI rates and correlates in TR-PCI versus transfemoral PCI (TF-PCI) in a propensity score-matched analysis of patient data from a large, single-center registry. We performed a 1:1 propensity score-matched analysis on consecutive patients who underwent PCI from January 2011 to June 2016, excluding those on dialysis. A multivariate logistic regression model was adjusted to variables found to be significant in univariate models. AKI was defined by creatinine increase of >0.3 mg/dL post-PCI during hospitalization. During the study period, 6,743 patients underwent PCI (TR-PCI n = 1,119). Initial univariate models revealed significant differences between patients with TF-PCI and TR-PCI. Contrast amount and procedure duration were both increased with TR-PCI versus TF-PCI (162 vs 154 ml, p = 0.003; and 86 vs 79 minutes, p <0.001, respectively). Multivariate propensity score analysis matched 536 pairs of patients. In this matched cohort, TR-PCI was associated with a reduced risk for AKI compared with TF-PCI in univariate (4.3% vs 10.4%, p <0.001) and multivariate adjusted models (odds ratio 0.28, 95% confidence interval 0.19 to 0.59, p <0.001).Abstract: Copyright (c) 2017 Elsevier Inc. All rights reserved.