MedStar Authors catalog › Details for: Patient characteristics in variable left ventricular recovery from Takotsubo syndrome.
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Patient characteristics in variable left ventricular recovery from Takotsubo syndrome.

by Kim, Jae I; Azzouqa, Alaa; Koiffman, Edward; Weissman, Gaby; Wang, Zuyue; Torguson, Rebecca; Satler, Lowell F; Pichard, Augusto D; Waksman, Ron; Lindsay, Joseph; Ben-Dor, Itsik.
Citation: Cardiovascular Revascularization Medicine. 19(3 Pt A):247-250, 2018 04..Journal: Cardiovascular revascularization medicine : including molecular interventions.Published: ; 2018ISSN: 1878-0938.Full author list: Kim JI; Yerasi C; Azzouqa A; Koiffman E; Weissman G; Wang Z; Moran J; Torguson R; Satler LF; Pichard AD; Waksman R; Lindsay J; Ben-Dor I.UI/PMID: 29153508.Subject(s): IN PROCESS -- NOT YET INDEXEDInstitution(s): MedStar Washington Hospital Center | MedStar Heart & Vascular InstituteDepartment(s): Medicine/Internal MedicineActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: (Click here) Abbreviated citation: Cardiovasc Revasc Med. 19(3 Pt A):247-250, 2018 04.Local Holdings: Available in print through MWHC library: 2002 - present.Abstract: BACKGROUND: Takotsubo syndrome (TTS) is a heart failure syndrome which is usually reversible. Factors associated with degree of recovery of left ventricular systolic function in TTS are poorly understood.Abstract: MATERIALS AND METHODS: We conducted a retrospective analysis of 90 TTS patients treated at our institution from 2006 to 2014. Patients were grouped based on recovery of left ventricular ejection fraction (LVEF) on follow-up transthoracic echocardiogram as left ventricular ejection fraction <50% (partial group) or preserved ejection fraction >=50% (full group). Patient baseline characteristics, comorbidities, biomarkers, electrocardiography, and echocardiogram were collected. We also compared adverse events that occurred during hospitalization.Abstract: RESULTS: In comparison to full recovery group patients (n=63), partial recovery patients (n=27) were older (76.9+/-13 vs. 70.6+/-13years; P=0.02) and had a higher prevalence of comorbid hypothyroidism (26% vs. 8%; P=0.02). A greater number of patients from the partial group were also taking levothyroxine replacement (22% vs. 3%; P=0.003). We found no significant between-group differences in type of triggering event or cardiac biomarker levels. QT interval was longer in the partial group (540.6+/-71msec vs. 460.7+/-35msec; P=0.01). Follow-up LVEF was 37.9+/-8% in the partial group and 58.0+/-4% in the full group (P<0.001). There were no statistically significant differences in length of stay or adverse events.Abstract: CONCLUSION: Takotsubo patients with partial myocardial recovery were older, presented with longer QT intervals, and were more likely to have comorbid hypothyroidism.Abstract: Copyright (c) 2017 Elsevier Inc. All rights reserved.

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