Protamine-induced acute thrombosis in a post-TAVR patient: A word of caution.

MedStar author(s):
Citation: Cardiovascular Revascularization Medicine. 2022 Jun 10PMID: 35779996Institution: MedStar Heart & Vascular Institute | MedStar Washington Hospital Center | MedStar Washington Hospital CenterDepartment: Internal Medicine Residency | Interventional Cardiology FellowshipForm of publication: Journal ArticleMedline article type(s): Case ReportsSubject headings: IN PROCESS -- NOT YET INDEXEDYear: 2022Local holdings: Available in print through MWHC library: 2002 - presentISSN:
  • 1878-0938
Name of journal: Cardiovascular revascularization medicine : including molecular interventionsAbstract: Major vascular complications after transcatheter aortic valve replacement (TAVR) are a pertinent issue and associated with increased morbidity and mortality. We herein describe a case of acute limb ischemia following the administration of protamine sulfate (PS) that was administered to mitigate a bleeding complication post-failure of a vascular access closure device. PS should be used cautiously for the prevention or management of bleeding-site complications following TAVR. The patient described in this case has consented to having his case described in this manuscript. Copyright © 2022. Published by Elsevier Inc.All authors: Bernardo NL, Bhogal S, Kallur AS, Waksman RFiscal year: FY2022Digital Object Identifier: Date added to catalog: 2022-09-26
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Journal Article MedStar Authors Catalog Article 35779996 Available 35779996

Available in print through MWHC library: 2002 - present

Major vascular complications after transcatheter aortic valve replacement (TAVR) are a pertinent issue and associated with increased morbidity and mortality. We herein describe a case of acute limb ischemia following the administration of protamine sulfate (PS) that was administered to mitigate a bleeding complication post-failure of a vascular access closure device. PS should be used cautiously for the prevention or management of bleeding-site complications following TAVR. The patient described in this case has consented to having his case described in this manuscript. Copyright © 2022. Published by Elsevier Inc.

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