MedStar Authors catalog › Details for: Scar quantification by cardiovascular magnetic resonance as an independent predictor of long-term survival in patients with ischemic heart failure treated by coronary artery bypass graft surgery.
Normal view MARC view ISBD view

Scar quantification by cardiovascular magnetic resonance as an independent predictor of long-term survival in patients with ischemic heart failure treated by coronary artery bypass graft surgery.

by Weissman, Gaby; Kancherla, Kalyan; Hill, Peter C; Boyce, Steven W.
Citation: Journal of Cardiovascular Magnetic Resonance. 18(1):45, 2016 Jul 18.Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.Published: 2016ISSN: 1097-6647.Full author list: Kancharla K; Weissman G; Elagha AA; Kancherla K; Samineni S; Hill PC; Boyce S; Fuisz AR.UI/PMID: 27430331.Subject(s): Aged | *Cardiomyopathies/dg [Diagnostic Imaging] | Cardiomyopathies/mo [Mortality] | Cardiomyopathies/pp [Physiopathology] | *Cicatrix/dg [Diagnostic Imaging] | Cicatrix/mo [Mortality] | Cicatrix/pp [Physiopathology] | Contrast Media/ad [Administration & Dosage] | Coronary Artery Bypass/ae [Adverse Effects] | Coronary Artery Bypass/mo [Mortality] | *Coronary Artery Bypass | Coronary Artery Disease/dg [Diagnostic Imaging] | Coronary Artery Disease/mo [Mortality] | *Coronary Artery Disease/su [Surgery] | Databases, Factual | Female | *Heart Failure/dg [Diagnostic Imaging] | Heart Failure/mo [Mortality] | Heart Failure/pp [Physiopathology] | Humans | Kaplan-Meier Estimate | *Magnetic Resonance Imaging, Cine | Male | Middle Aged | *Myocardial Infarction/dg [Diagnostic Imaging] | Myocardial Infarction/mo [Mortality] | Myocardial Infarction/pp [Physiopathology] | *Myocardium/pa [Pathology] | Predictive Value of Tests | Proportional Hazards Models | Recovery of Function | Retrospective Studies | Risk Factors | Stroke Volume | Time Factors | Treatment Outcome | Ventricular Function, LeftInstitution(s): MedStar Heart & Vascular Institute | MedStar Health Research Institute | MedStar Washington Hospital CenterDepartment(s): MedicineActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: https://dx.doi.org/10.1186/s12968-016-0265-y (Click here) Abbreviated citation: J Cardiovasc Magn Reson. 18(1):45, 2016 Jul 18.Local Holdings: Available online from MWHC library: 2008 - present.Abstract: BACKGROUND: Scar burden by late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) is associated with functional recovery after coronary artery bypass surgery (CABG). There is limited data on long-term mortality after CABG based on left ventricular (LV) scar burden.Abstract: METHODS: Patients who underwent LGE CMR between January 2003 and February 2010 within 1 month prior to CABG were included. A standard 16 segment model was used for scar quantification. A score of 1 for no scar, 2 for<50 % and 3 for>50 % transmurality was assigned for each segment. LV scar score (LVSS) defined as the sum of segment scores divided by 16. All-cause mortality was ascertained by social security death index.Abstract: RESULTS: One hundred ninety-six patients met the inclusion criteria. 185 CMR studies were available. History of prior MI was present in 64 % and prior CABG in 5.4 % of patients. Scar was present in 72 % of patients and median LVEF was 38 %. Over a median follow up of 8.3 years, there were 64 deaths (34.6 %). There was no statistically significant difference in mortality between Scar and No-scar groups (37 % versus 29 %). In the group with scar, a lower scar burden (defined either<4 segments with scar or based on LVSS) was independently associated with increased survival.Abstract: CONCLUSION: In patients undergoing surgical revascularization, scar burden is negatively associated with survival in patients with scar. However, there is no difference in survival based on presence or absence of scar alone. CMR prior to CABG adds additional prognostic information.

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