MedStar Authors catalog › Details for: Reference ranges for rotational thromboelastometry in male Sprague Dawley rats.
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Reference ranges for rotational thromboelastometry in male Sprague Dawley rats.

by Carney, Bonnie C; Chen, Jason H; Moffatt, Lauren T; Shupp, Jeffrey W.
Citation: Thrombosis Journal [Electronic Resource]. 15:31, 2017.Journal: Thrombosis journal.Published: 2017ISSN: 1477-9560.Full author list: Cruz MV; Luker JN; Carney BC; Brummel-Ziedins KE; Bravo MC; Orfeo T; Chen JH; Moffatt LT; Shupp JW.UI/PMID: 29299031.Subject(s): IN PROCESS -- NOT YET INDEXEDInstitution(s): MedStar Washington Hospital Center | MedStar Health Research InstituteDepartment(s): Surgery | Firefighters' Burn and Surgical Research LaboratoryActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: https://dx.doi.org/10.1186/s12959-017-0154-0 (Click here) Abbreviated citation: Thromb J. 15:31, 2017.Local Holdings: Available online through MWHC library: 2003 - present.Abstract: Background: A functional coagulation assay was used to investigate the extrinsic pathway of coagulation on citrated whole blood samples from healthy adult male Sprague Dawley rats using the mini cup and pin system.Abstract: Methods: Reference values for coagulation parameters from forty-three animals were calculated using data obtained from the ROTEM delta hemostasis analyzer with the EXTEM test.Abstract: Results: The following ranges, presented as the 2.5-97.5 percentiles, were established: CT [18-77], CFT [20-80], alpha [73-86], MCF [53-70], and ML [1-22], along with others.Abstract: Conclusions: These reference ranges can be used in future studies in rats to identify clinically significant coagulopathies.

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