MedStar Authors catalog › Details for: Induction of Labor in Women with Oligohydramnios: Misoprostol Compared with Prostaglandin E2.
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Induction of Labor in Women with Oligohydramnios: Misoprostol Compared with Prostaglandin E2.

by Kawakita, Tetsuya; Grantz, Katherine L; Landy, Helain J; Huang, Chun Chih.
Citation: American Journal of Perinatology. 34(2):204-210, 2017 Jan.Journal: American journal of perinatology.Published: 2017ISSN: 0735-1631.Full author list: Kawakita T; Grantz KL; Landy HJ; Huang CC; Kominiarek MA.UI/PMID: 27398704.Subject(s): Adult | Blood Transfusion | Cesarean Section | Chorioamnionitis/et [Etiology] | *Dinoprostone/tu [Therapeutic Use] | Female | Humans | Infant, Newborn | Intensive Care Units, Neonatal | *Labor, Induced/mt [Methods] | Length of Stay | *Misoprostol/tu [Therapeutic Use] | *Oligohydramnios/th [Therapy] | *Oxytocics | Patient Admission | Postpartum Hemorrhage/et [Etiology] | Pregnancy | Respiration, Artificial | Sepsis/et [Etiology] | Young AdultInstitution(s): MedStar Washington Hospital Center | MedStar Health Research InstituteDepartment(s): Obstetrics and Gynecology/Maternal-Fetal MedicineActivity type: Journal Article.Medline article type(s): Journal ArticleDigital Object Identifier: https://dx.doi.org/10.1055/s-0036-1585418 (Click here) Abbreviated citation: Am J Perinatol. 34(2):204-210, 2017 Jan.Abstract: <b>Objective</b> To compare perinatal outcomes in women with oligohydramnios and an unfavorable cervix undergoing labor induction with misoprostol to prostaglandin E2. <b>Study Design</b> We conducted a secondary analysis of women with oligohydramnios undergoing labor induction in the Consortium on Safe Labor study (2002-2008). Oligohydramnios was recorded in the medical chart. We evaluated perinatal outcomes. We limited the analysis to women with an unfavorable cervix defined by simplified Bishop score < 4. Misoprostol was compared with prostaglandin E2. Women could have received oxytocin, underwent mechanical dilation, or had artificial rupture of membranes, but women who underwent induction with both misoprostol and prostaglandin E2 were excluded. We calculated adjusted odds ratios with 95% confidence intervals, controlling for maternal age, maternal body mass index (kg/m<sup>2</sup>), parity, and mechanical dilation. <b>Results</b> Among women with oligohydramnios and an unfavorable cervix who underwent induction of labor, 141 (39.4%) received misoprostol and 217 (60.6%) received prostaglandin E2. There were no significant differences in cesarean delivery, chorioamnionitis, postpartum hemorrhage, transfusion, neonatal intensive care unit (NICU) admission, NICU stay>72 hours, mechanical ventilation, and neonatal sepsis. <b>Conclusion</b> In women with oligohydramnios and an unfavorable cervix, induction of labor with misoprostol was comparable to prostaglandin E2.Abstract: Copyright Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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