Citation: Medicine. 97(11):e9944, 2018 Mar.Journal: Medicine.Published: 2018ISSN: 0025-7974.Full author list: Yunce M; Sharma A; Braunstein E; Streiff MB; Lum YW.UI/PMID: 29538219.Subject(s): IN PROCESS -- NOT YET INDEXEDInstitution(s): Medstar Franklin Square Medical CenterDepartment(s): MedicineActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access onlineDigital Object Identifier: https://dx.doi.org/10.1097/MD.0000000000009944 (Click here)Abbreviated citation: Medicine (Baltimore). 97(11):e9944, 2018 Mar.Local Holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006.Abstract: RATIONALE: Thoracic outlet syndrome (TOS) is a rare cause of upper extremity deep vein thrombosis (UEDVT). The treatment usually involves catheter directed thrombolysis followed by systemic anticoagulation. Surgical decompression is frequently recommended after anticoagulation for definitive therapy.Abstract: PATIENT CONCERNS: We report two cases of UEDVT secondary to venous TOS with important clinical presentations.Abstract: DIAGNOSES: Venous TOS.Abstract: INTERVENTIONS: One patient was initially treated conservatively but had a recurrent UEDVT. The second patient had a residual stump from a prior rib resection that was causing compression on the subclavian vein, resulting in recurrent venous symptoms.Abstract: OUTCOMES: Both patients achieved significant improvement in their symptoms at 1 year follow-up.Abstract: LESSONS: UEDVTs can be debilitating, and may limit activities of daily living. Surgical decompression may offer significant improvement in quality of life and symptom relief in such patients.