Citation: Case Reports Gastroenterology. 11(3):780-785, 2017 Sep-Dec.Journal: Case reports in gastroenterology.Published: 2017ISSN: 1662-0631.Full author list: Nazari M; Lee A; Rosenblum J; Baba T; Kallus S.UI/PMID: 29606935.Institution(s): MedStar Washington Hospital CenterDepartment(s): Medicine/Pediatrics | Medicine/GastroenterologyActivity type: Journal Article.Medline article type(s): Journal Article | ReviewDigital Object Identifier: https://dx.doi.org/10.1159/000485238 (Click here)Abbreviated citation: Case rep., gastroenterol.. 11(3):780-785, 2017 Sep-Dec.Abstract: Primary adenocarcinoma of the small intestine comprises one of the rarest gastrointestinal malignancies. Further, the terminal ileum is very seldom implicated. This entity occurs sporadically and evades traditional colonoscopic evaluation in which the terminal ileum is not visualized. Herein, a case of interval development of primary terminal ileal adenocarcinoma over a 2-year period is reported as followed by direct endoscopic and colonoscopic visualization. This case demonstrates cecal involvement not found on initial evaluation without the provision of terminal ileum intubation. Relevant guidelines regarding the evaluation of the terminal ileum in routine colonoscopy are reviewed.