Burn-Induced Coagulopathies: a Comprehensive Review. [Review]

MedStar author(s):
Citation: Shock. 54(2):154-167, 2020 08.PMID: 31804296Institution: MedStar Health Research Institute | MedStar Washington Hospital CenterDepartment: Firefighters' Burn and Surgical Research Laboratory | Surgery/Burn ServicesForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Blood Coagulation Disorders/et [Etiology] | *Burns/co [Complications] | Blood Coagulation Disorders/di [Diagnosis] | Female | Fibrinolysis/ph [Physiology] | Humans | Inflammation/pp [Physiopathology] | MaleYear: 2020Local holdings: Available online through MWHC library: 2002 - presentISSN:
  • 1073-2322
Name of journal: Shock (Augusta, Ga.)Abstract: Burn-induced coagulopathy is not well understood, and consensus on diagnosis, prevention, and treatments are lacking. In this review, literature on burn-induced (and associated) coagulopathy is presented along with the current understanding of the effects of burn injury on the interactions among coagulation, fibrinolysis, and inflammation in the acute resuscitative phase and reconstructive phase of care. The role of conventional tests of coagulopathy and functional assays like thromboelastography or thromboelastometry will also be discussed. Finally, reported methods for the prevention and treatment of complications related to burn-induced coagulopathy will be reviewed.All authors: Ball RL, Brummel-Ziedins K, Johnson LS, Keyloun JW, Moffatt LT, Orfeo T, Palmieri TL, Pusateri AE, Shupp JWOriginally published: Shock. 2019 Nov 19Fiscal year: FY2021Fiscal year of original publication: FY2020Digital Object Identifier: Date added to catalog: 2020-01-03
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 31804296 Available 31804296

Available online through MWHC library: 2002 - present

Burn-induced coagulopathy is not well understood, and consensus on diagnosis, prevention, and treatments are lacking. In this review, literature on burn-induced (and associated) coagulopathy is presented along with the current understanding of the effects of burn injury on the interactions among coagulation, fibrinolysis, and inflammation in the acute resuscitative phase and reconstructive phase of care. The role of conventional tests of coagulopathy and functional assays like thromboelastography or thromboelastometry will also be discussed. Finally, reported methods for the prevention and treatment of complications related to burn-induced coagulopathy will be reviewed.

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