Orthopaedic Manifestations of Melanoma and Their Management. [Review]

MedStar author(s):
Citation: Journal of the American Academy of Orthopaedic Surgeons. 28(13):e540-e549, 2020 Jul 01.PMID: 32097135Institution: MedStar Union Memorial HospitalDepartment: Orthopaedic SurgeryForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Bone Neoplasms/sc [Secondary] | *Melanoma/sc [Secondary] | *Muscle Neoplasms/sc [Secondary] | *Orthopedics | *Skin Neoplasms/pa [Pathology] | *Skin/pa [Pathology] | Biopsy | Bone Neoplasms/di [Diagnosis] | Bone Neoplasms/pa [Pathology] | Bone Neoplasms/th [Therapy] | Diagnosis, Differential | Humans | Melanoma/di [Diagnosis] | Melanoma/pa [Pathology] | Melanoma/th [Therapy] | Muscle Neoplasms/di [Diagnosis] | Muscle Neoplasms/pa [Pathology] | Muscle Neoplasms/th [Therapy] | Orthopedic Surgeons | Physical Examination | Prognosis | Skin Neoplasms/di [Diagnosis] | Skin Neoplasms/th [Therapy]Year: 2020Local holdings: Available online from MWHC library: Oct 1993 - present, Available in print through MWHC library: 1999 - presentISSN:
  • 1067-151X
Name of journal: The Journal of the American Academy of Orthopaedic SurgeonsAbstract: Melanoma is an aggressive form of skin cancer associated with significant morbidity and mortality. Although commonly seen in dermatologist clinics, orthopaedic surgeons must be aware of these lesions in various ways. The five common musculoskeletal manifestations of melanoma will be discussed as well as the epidemiology, pathogenesis, diagnosis, staging, treatment, and prognosis of melanoma. With an index of suspicion and awareness of melanoma, a thorough history and detailed physical examination are critical in establishing a diagnosis. An adequately performed biopsy will confirm the diagnosis and assist in determining prognosis. As ambassadors of health for the musculoskeletal system, orthopaedic surgeons may be the first practitioners to encounter a pigmented skin lesion. Acral pigmented lesions should prompt a concern for melanoma with appropriate subsequent steps for management to follow. Finally, it is important for every orthopaedic surgeon to consider disseminated melanoma in the differential diagnosis of a skeletal metastasis, a deep soft-tissue mass, or lymphadenopathy in a patient with a previous history of a melanotic lesion.All authors: Abousayed MM, DiCaprio MR, Kambam MLROriginally published: Journal of the American Academy of Orthopaedic Surgeons. 2020 Feb 24Fiscal year: FY2020Digital Object Identifier: Date added to catalog: 2020-02-28
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Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 32097135 Available 32097135

Available online from MWHC library: Oct 1993 - present, Available in print through MWHC library: 1999 - present

Melanoma is an aggressive form of skin cancer associated with significant morbidity and mortality. Although commonly seen in dermatologist clinics, orthopaedic surgeons must be aware of these lesions in various ways. The five common musculoskeletal manifestations of melanoma will be discussed as well as the epidemiology, pathogenesis, diagnosis, staging, treatment, and prognosis of melanoma. With an index of suspicion and awareness of melanoma, a thorough history and detailed physical examination are critical in establishing a diagnosis. An adequately performed biopsy will confirm the diagnosis and assist in determining prognosis. As ambassadors of health for the musculoskeletal system, orthopaedic surgeons may be the first practitioners to encounter a pigmented skin lesion. Acral pigmented lesions should prompt a concern for melanoma with appropriate subsequent steps for management to follow. Finally, it is important for every orthopaedic surgeon to consider disseminated melanoma in the differential diagnosis of a skeletal metastasis, a deep soft-tissue mass, or lymphadenopathy in a patient with a previous history of a melanotic lesion.

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