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The evolving role of coronary computed tomography in understanding sex differences in coronary atherosclerosis. [Review]

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Citation: Journal of cardiovascular computed tomography. 16(2):138-149, 2022 Mar-Apr.PMID: 34654676Institution: MedStar Union Memorial HospitalForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Coronary Artery Disease | *Plaque, Atherosclerotic | Computed Tomography Angiography | Coronary Angiography/mt [Methods] | Coronary Artery Disease/dg [Diagnostic Imaging] | Female | Humans | Male | Predictive Value of Tests | Sex Characteristics | Tomography, X-Ray ComputedYear: 2022 ISSN:

1876-861X

Name of journal: Journal of cardiovascular computed tomographyAbstract: Our understanding of sex differences in subclinical atherosclerosis and plaque composition and characteristics have greatly improved with the use of coronary computed tomography (CCTA) over the past years. CCTA has emerged as an important frontline diagnostic test for women, especially as we continue to understand the impact of non-obstructive atherosclerosis as well as diffuse, high risk plaque as precursors of acute cardiac events in women. Based on its ability to identify complex plaque morphology such as low attenuation plaque, high risk non calcified plaque, positive remodeling, fibrous cap, CCTA can be used to assess plaque characteristics. CCTA can avoid false positive of other imaging studies, if included earlier in assessment of ischemic symptoms. In the contemporary clinical setting, CCTA will prove useful in further understanding and managing cardiovascular disease in women and those without traditional obstructive coronary disease. Copyright © 2021 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.All authors: Aggarwal NR, Blaha MJ, Blumenthal RS, Douglas PS, Garg K, Kanwal A, Nasir K, Patel TR, Sharma G, Shaw LJ, Villines TCFiscal year: FY2022 Digital Object Identifier:

https://dx.doi.org/10.1016/j.jcct.2021.09.004

Date added to catalog: 2022-05-16

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Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	34654676	Available		34654676

Our understanding of sex differences in subclinical atherosclerosis and plaque composition and characteristics have greatly improved with the use of coronary computed tomography (CCTA) over the past years. CCTA has emerged as an important frontline diagnostic test for women, especially as we continue to understand the impact of non-obstructive atherosclerosis as well as diffuse, high risk plaque as precursors of acute cardiac events in women. Based on its ability to identify complex plaque morphology such as low attenuation plaque, high risk non calcified plaque, positive remodeling, fibrous cap, CCTA can be used to assess plaque characteristics. CCTA can avoid false positive of other imaging studies, if included earlier in assessment of ischemic symptoms. In the contemporary clinical setting, CCTA will prove useful in further understanding and managing cardiovascular disease in women and those without traditional obstructive coronary disease. Copyright © 2021 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.

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