MedStar Authors catalog › Details for: Hospital readmission with Clostridium difficile infection as a secondary diagnosis is associated with worsened outcomes and greater revenue loss relative to principal diagnosis: A retrospective cohort study.
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Hospital readmission with Clostridium difficile infection as a secondary diagnosis is associated with worsened outcomes and greater revenue loss relative to principal diagnosis: A retrospective cohort study.

by Shorr, Andrew F.
Citation: Medicine. 97(36):e12212, 2018 Sep..Journal: Medicine.Published: ; 2018ISSN: 0025-7974.Full author list: Zilberberg MD; Nathanson BH; Marcella S; Hawkshead JJ 3rd; Shorr AF.UI/PMID: 30200134.Subject(s): Adolescent | Adult | Aged | *Clostridium Infections/di [Diagnosis] | Clostridium Infections/ec [Economics] | Clostridium Infections/mo [Mortality] | *Clostridium Infections/th [Therapy] | Female | Follow-Up Studies | Health Care Costs | Hospital Mortality | Humans | Length of Stay/ec [Economics] | Male | Middle Aged | Patient Readmission/ec [Economics] | *Patient Readmission | Retrospective Studies | United States | Young AdultInstitution(s): MedStar Washington Hospital CenterDepartment(s): Medicine/Pulmonary-Critical CareActivity type: Journal Article.Medline article type(s): Comparative Study | Journal Article | Multicenter Study | Observational StudyDigital Object Identifier: https://dx.doi.org/10.1097/MD.0000000000012212 (Click here) Abbreviated citation: Medicine (Baltimore). 97(36):e12212, 2018 Sep.Local Holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006.Abstract: Recurrent Clostridium difficile infection (rCDI) requiring rehospitalization contributes to poor outcomes, which may differ between patients hospitalized with versus for it.We performed a multicenter retrospective cohort study of rehospitalized adults surviving initial CDI hospitalization. Hospital mortality, length of stay (LOS), 30-day readmission, and mean gap between hospital costs and Diagnosis Related Group (DRG) reimbursement served as outcomes.Among the 25.7% (n = 99,175) survivors requiring rehospitalization, 36,504 (36.8%) had rCDI (14,005 [38.4%] principal diagnosis rCDI [PrCDI]). Compared with non-CDI, PrCDI, and secondary diagnosis rCDI [SrCDI] carried lower risk of death (PrCDI odds ratio [OR] 0.52; 95% confidence interval [CI] 0.46, 0.58; SrCDI OR 0.80; 95% CI 0.75, 0.85) and 30-day readmission (PrCDI OR 0.84; 95% CI 0.80, 0.88; SrCDI OR 0.97; 95% CI 0.94, 1.01), and excess LOS (PrCDI 1.8 days; 95% CI 1.7, 2.0; SrCDI 1.4 days; 95% CI 1.3, 1.5), and costs (PrCDI

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