Gastrointestinal Bleeding among Hospitalizations for Salicylate Poisoning in the United States.

MedStar author(s):
Citation: Qjm. 114(3):190-195, 2021 May 19.PMID: 33599273Institution: MedStar Washington Hospital CenterDepartment: Medicine/GastroenterologyForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Gastrointestinal Hemorrhage | *Hospitalization | Databases, Factual | Gastrointestinal Hemorrhage/ci [Chemically Induced] | Hospital Mortality | Humans | Retrospective Studies | Salicylates | United StatesYear: 2021Local holdings: Available online from MWHC library: 1995 - presentISSN:
  • 1460-2393
Name of journal: QJM : monthly journal of the Association of PhysiciansAbstract: BACKGROUND: This study aimed to determine the incidence, as well as evaluate risk factors, and impact of gastrointestinal bleeding on outcomes and resource use in patients admitted for salicylate poisoning.CONCLUSION: Gastrointestinal bleeding occurred in about 4% of patients admitted for salicylate poisoning. Gastrointestinal bleeding was associated with higher morbidity and resource use but not mortality. Copyright (c) The Author(s) 2021. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]: We used the National Inpatient Sample to construct a cohort of patients hospitalized primarily for salicylate poisoning from 2003-2014. We compared clinical characteristics, in-hospital treatments, outcomes, and resource use between salicylate poisoning patients with and without gastrointestinal bleeding.RESULTS: Of 13,805 hospital admissions for salicylate poisoning, gastrointestinal bleeding occurred in 482 (3.5%) admissions. The risk factors for gastrointestinal bleeding included older age, history of atrial fibrillation, and cirrhosis. After adjusting for difference in baseline characteristics, patients with gastrointestinal bleeding required more gastric lavage, gastrointestinal endoscopy, invasive mechanical ventilation, red blood cell transfusion. Gastrointestinal bleeding was significantly associated with increased risk of anemia, circulatory, liver, and hematological failure but was not significantly associated with increased in-hospital mortality. The length of hospital stay and hospitalization cost was significantly higher in patients with gastrointestinal bleeding.All authors: Bathini T, Boonpheng B, Cheungpasitporn W, Choudhury A, Kaewput W, Lapumnuaypol K, Mao MA, Petnak T, Qureshi F, Thongprayoon C, Vallabhajosyula SOriginally published: Qjm. 2021 Feb 18Fiscal year: FY2021Digital Object Identifier: Date added to catalog: 2021-03-10
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 33599273 Available 33599273

Available online from MWHC library: 1995 - present

BACKGROUND: This study aimed to determine the incidence, as well as evaluate risk factors, and impact of gastrointestinal bleeding on outcomes and resource use in patients admitted for salicylate poisoning.

CONCLUSION: Gastrointestinal bleeding occurred in about 4% of patients admitted for salicylate poisoning. Gastrointestinal bleeding was associated with higher morbidity and resource use but not mortality. Copyright (c) The Author(s) 2021. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected].

METHODS: We used the National Inpatient Sample to construct a cohort of patients hospitalized primarily for salicylate poisoning from 2003-2014. We compared clinical characteristics, in-hospital treatments, outcomes, and resource use between salicylate poisoning patients with and without gastrointestinal bleeding.

RESULTS: Of 13,805 hospital admissions for salicylate poisoning, gastrointestinal bleeding occurred in 482 (3.5%) admissions. The risk factors for gastrointestinal bleeding included older age, history of atrial fibrillation, and cirrhosis. After adjusting for difference in baseline characteristics, patients with gastrointestinal bleeding required more gastric lavage, gastrointestinal endoscopy, invasive mechanical ventilation, red blood cell transfusion. Gastrointestinal bleeding was significantly associated with increased risk of anemia, circulatory, liver, and hematological failure but was not significantly associated with increased in-hospital mortality. The length of hospital stay and hospitalization cost was significantly higher in patients with gastrointestinal bleeding.

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