MedStar Authors catalog › Details for: Balloon Retrograde Transvenous Obliteration Versus Endoscopic Cyanoacrylate in Bleeding Gastric Varices: Comparison of Rebleeding and Mortality with Extended Follow-up.
Balloon Retrograde Transvenous Obliteration Versus Endoscopic Cyanoacrylate in Bleeding Gastric Varices: Comparison of Rebleeding and Mortality with Extended Follow-up. Journal: Journal of vascular and interventional radiology : JVIR. Published: ; 2019 ISSN: 1051-0443. UI/PMID: 30717949. Subject(s): Adult | Aged | Balloon Occlusion/ae [Adverse Effects] | Balloon Occlusion/mo [Mortality] | *Balloon Occlusion | *Enbucrilate/ad [Administration & Dosage] | Enbucrilate/ae [Adverse Effects] | Esophageal and Gastric Varices/di [Diagnosis] | Esophageal and Gastric Varices/et [Etiology] | Esophageal and Gastric Varices/mo [Mortality] | *Esophageal and Gastric Varices/th [Therapy] | Female | Follow-Up Studies | Gastrointestinal Hemorrhage/di [Diagnosis] | Gastrointestinal Hemorrhage/et [Etiology] | Gastrointestinal Hemorrhage/mo [Mortality] | *Gastrointestinal Hemorrhage/th [Therapy] | Hemostasis, Endoscopic/ae [Adverse Effects] | *Hemostasis, Endoscopic/mt [Methods] | Hemostasis, Endoscopic/mo [Mortality] | Humans | Hypertension, Portal/co [Complications] | Hypertension, Portal/mo [Mortality] | Male | Middle Aged | Recurrence | Retrospective Studies | Risk Factors | Time Factors | Treatment Outcome Institution(s): MedStar Washington Hospital Center Department(s): Radiology Activity type: Journal Article. Medline article type(s): Journal Article Online resources: Click here to access online Digital Object Identifier: https://dx.doi.org/10.1016/j.jvir.2018.12.008 (Click here) Abbreviated citation: J Vasc Interv Radiol. 30(2):187-194, 2019 Feb. Local Holdings: Available online through MWHC library: 2002 - 2006, Available in print through MWHC library: 1999 - 2006. Abstract: PURPOSE: To assess short- and long-term mortality and rebleeding with endoscopic cyanoacrylate (EC) versus balloon-occluded retrograde transvenous obliteration (BRTO). Abstract: MATERIALS AND METHODS: A retrospective cohort comparison was conducted of 90 EC patients and 71 BRTO patients from 1997 through 2015 with portal hypertension who presented due to endoscopically confirmed bleeding cardiofundal gastric varices. Patients underwent either endoscopic intra-varix injection of 4-carbon-n-butyl-2-cyanoacrylate or sclerosis with sodium tetradecyl sulfate with balloon occlusion for primary variceal treatment. Abstract: RESULTS: Seventy-one BRTO patients and 90 EC patients, of whom 89% had cirrhosis and 35% were women, were included, with a respective average Model for End-Stage Liver Disease (MELD) score of 13.4 and 14.4, respectively. Mortality at 6 weeks was 14.4% for EC patients and 13.1% for BRTO patients (Kaplan-Meier/Wilcoxon, P = .85). No long-term mortality difference was observed (Cox hazard ratio [HR] = 0.89, P = .64). Also, 5.1% of EC patients and 3.5% of BRTO patients (Kaplan-Meier/Wilcoxon, P = .62) rebled at 6 weeks, but at 1 year, 22.0% of EC patients and 3.5% of BRTO patients had rebled (Kaplan-Meier/Wilcoxon, P < .01). Lower rates of long-term rebleeding were found with BRTO (Cox HR = 0.25, P = .03). No difference was seen in the rate of new portal hypertensive complications (Cox HR = 1.21, P = .464). However, 16/71 patients who underwent BRTO had simultaneous transjugular intrahepatic portosystemic shunt. Age, sex, MELD score, and presence of cirrhosis were the primary predictors of mortality. One death in the EC group and 5 deaths in the BRTO group were deemed to be procedurally related (chi-square, P = .088). Abstract: CONCLUSIONS: BRTO is associated with a lower rate of rebleeding but no change in mortality.
Abstract: Copyright (c) 2018 SIR. Published by Elsevier Inc. All rights reserved.