MedStar Authors catalog › Details for: Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis and Prior External Chest Radiation.
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Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis and Prior External Chest Radiation.

by Attaran, Saina; Ben-Dor, Itsik; Buchanan, Kyle; Gajanana, Deepakraj; Iantorno, Micaela; Kolm, Paul; Okubagzi, Petros; Rogers, Toby; Satler, Lowell F; Thourani, Vinod H; Torguson, Rebecca; Waksman, Ron; Weintraub, William S; Zhang, Cheng.
Citation: ; Cardiovascular Revascularization Medicine. 20(5):376-380, 2019 05..Journal: Cardiovascular revascularization medicine : including molecular interventions.Published: ; 2019; ISSN: 1878-0938.Full author list: Attaran S; Ben-Dor I; Buchanan KD; Gajanana D; Iantorno M; Kolm P; Okubagzi PG; Rogers T; Satler LF; Thourani VH; Torguson R; Waksman R; Weintraub WS; Zhang C.UI/PMID: 31079816.Subject(s): Aged | Treatment Outcome | *Transcatheter Aortic Valve Replacement | Transcatheter Aortic Valve Replacement/mo [Mortality] | Transcatheter Aortic Valve Replacement/ae [Adverse Effects] | Time Factors | *Thorax/re [Radiation Effects] | Severity of Illness Index | Risk Factors | Radiotherapy | Prospective Studies | Prevalence | Middle Aged | Male | Length of Stay | Humans | Hemodynamics | Heart Block/th [Therapy] | Heart Block/ep [Epidemiology] | Female | District of Columbia/ep [Epidemiology] | *Cancer Survivors | *Aortic Valve Stenosis/su [Surgery] | Aortic Valve Stenosis/pp [Physiopathology] | Aortic Valve Stenosis/mo [Mortality] | Aortic Valve Stenosis/dg [Diagnostic Imaging] | *Aortic Valve/su [Surgery] | Aortic Valve/pp [Physiopathology] | Aortic Valve/dg [Diagnostic Imaging] | Aged, 80 and overInstitution(s): MedStar Heart & Vascular InstituteActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: https://dx.doi.org/10.1016/j.carrev.2019.02.015 (Click here) Abbreviated citation: ; Cardiovasc Revasc Med. 20(5):376-380, 2019 05.Local Holdings: Available in print through MWHC library: 2002 - present.Abstract: BACKGROUND/PURPOSE: Surgical aortic valve replacement (SAVR) in patients with symptomatic severe aortic stenosis (AS) and prior chest radiation is associated with poor outcomes in comparison with patients without prior radiation. Our objective was to compare clinical outcomes of patients with and without prior chest radiation undergoing transcatheter aortic valve replacement (TAVR) for symptomatic severe AS.Abstract: CONCLUSIONS: Thus, TAVR appears to be a safe treatment option in the short and medium term for patients with symptomatic severe AS and prior chest radiation.Abstract: Copyright (c) 2019. Published by Elsevier Inc.Abstract: METHODS/MATERIALS: Between January 2003 and January 2017, 1150 patients underwent TAVR at our institution. Of these, 44 had prior chest radiation. Baseline demographic and clinical characteristics, procedural details, and clinical outcomes were prospectively collected.Abstract: RESULTS: Patients with prior chest radiation were younger, 76+/-13years, compared with those without prior chest radiation, 82+/-8years (p=0.002). Median Society of Thoracic Surgeons score for chest radiation patients was 7+/-4, compared to 8+/-5 in those without prior radiation. Despite higher prevalence of complete heart block, there was no significant difference between the 2 groups with regard to the need for permanent pacemaker implantation. There was a trend toward longer length of intensive care unit stay in chest radiation patients, but there was no significant difference in 30-day or 1-year mortality.

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