Seattle Angina Pectoris Questionnaire and Canadian Cardiovascular Society Angina Categories in the Assessment of Total Coronary Atherosclerotic Burden.

MedStar author(s):
Citation: American Journal of Cardiology. 152:43-48, 2021 08 01.PMID: 34175106Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Angina Pectoris/pp [Physiopathology] | *Atherosclerosis/pp [Physiopathology] | *Coronary Angiography | *Coronary Artery Disease/pp [Physiopathology] | *Percutaneous Coronary Intervention | Aged | Angina Pectoris/dg [Diagnostic Imaging] | Atherosclerosis/dg [Diagnostic Imaging] | Atherosclerosis/su [Surgery] | Coronary Artery Disease/dg [Diagnostic Imaging] | Coronary Artery Disease/su [Surgery] | Female | Humans | Male | Middle Aged | Patient Reported Outcome Measures | Prognosis | Prospective Studies | Severity of Illness Index | Surveys and QuestionnairesYear: 2021Local holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006ISSN:
  • 0002-9149
Name of journal: The American journal of cardiologyAbstract: The patient reported angina measurement with the Seattle Angina Questionnaire (SAQ) has shown to have prognostic implications and became an endpoint in clinical trials. Our objective was to study physician-reported and SAQ severity with the total coronary atherosclerotic burden as assessed by 4 angiographic scores. We prospectively analyzed data of consecutive patients scheduled for coronary angiography or percutaneous coronary intervention. The Canadian Cardiovascular Society (CCS) angina categories was used as physician-reported angina. SAQ domains were categorized as severe (0 to 24), moderate 25 to 75 and mild angina (>75). All angina assessments were done before coronary angiography. Gensini, Syntax, Friesinger, and Sullivan angiographic scores were used for total atherosclerotic burden quantification: 261 patients were included in the present analysis. The median age was 66.0 (59.0 to 71.8) years, 53.6% were male and 43.7% had diabetes. The median SYNTAX score was 6.0 (0 to 18.0). The worse the symptoms of CCS categories, the more severe was the atherosclerotic burden in all angiographic scores: SYNTAX (p=0.01); Gensini (p <0.01); Friesinger (p = 0.02) and Sullivan (p=0.03). Conversely, SAQ domains were not able to discriminate the severity of CAD in any of the scores. The only exception was the severe SAQ quality of life that had worse Gensini score than the mild SAQ quality of life (p=0.04). In conclusion, CCS angina categories are related to the total atherosclerotic burden in coronary angiography, by all angiographic scores. SAQ domains should be used as a measure of patient functionality and quality of life but not as a measure of CAD severity. Copyright (c) 2021 Elsevier Inc. All rights reserved.All authors: Abizaid A, Brito FS Jr, Campos CM, Filho RK, Garcia-Garcia HM, Guimaraes WVN, Hajjar L, Lemos PA, Mehta S, Nicz PFG, Ribeiro E, Ribeiro MH, Rosa VE, Santos LMOriginally published: American Journal of Cardiology. 2021 Jun 23Fiscal year: FY2022Fiscal year of original publication: FY2021Digital Object Identifier: Date added to catalog: 2021-07-19
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Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 34175106 Available 34175106

Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006

The patient reported angina measurement with the Seattle Angina Questionnaire (SAQ) has shown to have prognostic implications and became an endpoint in clinical trials. Our objective was to study physician-reported and SAQ severity with the total coronary atherosclerotic burden as assessed by 4 angiographic scores. We prospectively analyzed data of consecutive patients scheduled for coronary angiography or percutaneous coronary intervention. The Canadian Cardiovascular Society (CCS) angina categories was used as physician-reported angina. SAQ domains were categorized as severe (0 to 24), moderate 25 to 75 and mild angina (>75). All angina assessments were done before coronary angiography. Gensini, Syntax, Friesinger, and Sullivan angiographic scores were used for total atherosclerotic burden quantification: 261 patients were included in the present analysis. The median age was 66.0 (59.0 to 71.8) years, 53.6% were male and 43.7% had diabetes. The median SYNTAX score was 6.0 (0 to 18.0). The worse the symptoms of CCS categories, the more severe was the atherosclerotic burden in all angiographic scores: SYNTAX (p=0.01); Gensini (p <0.01); Friesinger (p = 0.02) and Sullivan (p=0.03). Conversely, SAQ domains were not able to discriminate the severity of CAD in any of the scores. The only exception was the severe SAQ quality of life that had worse Gensini score than the mild SAQ quality of life (p=0.04). In conclusion, CCS angina categories are related to the total atherosclerotic burden in coronary angiography, by all angiographic scores. SAQ domains should be used as a measure of patient functionality and quality of life but not as a measure of CAD severity. Copyright (c) 2021 Elsevier Inc. All rights reserved.

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