Vaginal Complications after Radical Cystectomy for Bladder Cancer: A Systematic Review.
Citation: Urology. 156:e20-e29, 2021 Oct.PMID: 34284007Institution: MedStar Washington Hospital CenterDepartment: Obstetrics and Gynecology/Urogynecology | Urology Residency AdvancedForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Cystectomy/ae [Adverse Effects] | *Postoperative Complications/et [Etiology] | *Urinary Bladder Neoplasms/su [Surgery] | *Vaginal Diseases/et [Etiology] | Female | HumansYear: 2021Local holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007Abstract: CONCLUSIONS: There is a need for more prospective studies, using standardized instruments and subjective outcome measures to better define the incidence of vaginal complications after radical cystectomy for bladder cancer, and to understand their impact on quality of life measures. Copyright (c) 2021. Published by Elsevier Inc.METHODS: Ovid MEDLINE, Ovid EMBASE, and Web of Science were systematically searched from January 1, 2001 to January 25, 2021 using a combination of search terms for bladder cancer and radical cystectomy with terms for four categories of vaginal complications (prolapse, fistula, evisceration/dehiscence, and dyspareunia). A total of 229 publications were identified, the final review included 28 publications.OBJECTIVES: To summarize the published literature regarding pelvic organ prolapse, dehiscence or evisceration, vaginal fistula, and dyspareunia after radical cystectomy and to describe the management approaches used to treat these conditions.RESULTS: Neobladder vaginal fistula was evaluated in 17 publications, with an incidence rate of 3-6% at higher volume centers, often along the anterior vaginal wall at the location of the neobladder-urethral anastomosis. Sexual function was evaluated in ten studies, seven of which utilized validated instruments. Maintaining the anterior vaginal wall and the distal urethra appeared to be associated with improved sexual function. Pelvic organ prolapse was assessed in five studies, only one used a validated questionnaire and none included a validated objective measure of pelvic organ support.Originally published: Urology. 2021 Jul 17Fiscal year: FY2022Digital Object Identifier: Date added to catalog: 2021-07-26| Item type | Current library | Collection | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|---|
| Journal Article | MedStar Authors Catalog | Article | 34284007 | Available | 34284007 |
Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007
CONCLUSIONS: There is a need for more prospective studies, using standardized instruments and subjective outcome measures to better define the incidence of vaginal complications after radical cystectomy for bladder cancer, and to understand their impact on quality of life measures. Copyright (c) 2021. Published by Elsevier Inc.
METHODS: Ovid MEDLINE, Ovid EMBASE, and Web of Science were systematically searched from January 1, 2001 to January 25, 2021 using a combination of search terms for bladder cancer and radical cystectomy with terms for four categories of vaginal complications (prolapse, fistula, evisceration/dehiscence, and dyspareunia). A total of 229 publications were identified, the final review included 28 publications.
OBJECTIVES: To summarize the published literature regarding pelvic organ prolapse, dehiscence or evisceration, vaginal fistula, and dyspareunia after radical cystectomy and to describe the management approaches used to treat these conditions.
RESULTS: Neobladder vaginal fistula was evaluated in 17 publications, with an incidence rate of 3-6% at higher volume centers, often along the anterior vaginal wall at the location of the neobladder-urethral anastomosis. Sexual function was evaluated in ten studies, seven of which utilized validated instruments. Maintaining the anterior vaginal wall and the distal urethra appeared to be associated with improved sexual function. Pelvic organ prolapse was assessed in five studies, only one used a validated questionnaire and none included a validated objective measure of pelvic organ support.
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