Comparison of the GenCut Core Biopsy System to Transbronchial Biopsy Forceps for Flexible Bronchoscopic Lung Biopsy.

MedStar author(s):
Citation: Journal of Bronchology & Interventional Pulmonology. 29(2):140-145, 2022 Apr 01.PMID: 35318988Department: MedStar Georgetown University Hospital/MedStar Washington Hospital Center | Pulmonary Disease & Critical Care Medicine FellowshipForm of publication: Journal ArticleMedline article type(s): Journal Article | Observational StudySubject headings: *Bronchoscopy | *Lung Neoplasms | Biopsy, Fine-Needle | Biopsy, Fine-Needle | Biopsy, Large-Core Needle | Bronchoscopy/mt [Methods] | Humans | Lung Neoplasms/di [Diagnosis] | Lung Neoplasms/pa [Pathology] | Lung/pa [Pathology] | Surgical InstrumentsYear: 2022ISSN:
  • 1948-8270
Name of journal: Journal of bronchology & interventional pulmonologyAbstract: BACKGROUND: Pulmonary nodules are increasingly detected on screening and routine chest imaging, leading to an increase in diagnostic procedures. Bronchoscopy with transbronchial biopsy (TBBx) is the most common diagnostic modality, with diagnostic yield between 43% and 86%, largely dependent on the use of navigational modalities. In 2015 a new biopsy tool by Medtronic, the GenCut core biopsy system [GenCut transbronchial needle aspiration (TBNA)], was developed with the intention of improving yield in lung nodule biopsies. Our goal was to determine the efficacy of this new device when used in addition to TBBx.CONCLUSION: The diagnostic yield is improved by using the GenCut core biopsy system in addition to traditional TBBx forceps when performing bronchoscopy for pulmonary nodules, without an increase in complications. These biopsy methods should be used in tandem for the greatest yield. Copyright ♭ 2021 Wolters Kluwer Health, Inc. All rights reserved.PATIENTS AND METHODS: This is a prospective observational study of 324 consecutive bronchoscopic lung biopsies in which both TBBx and GenCut TBNA were performed on the same lesion. We recorded patient and nodule characteristics, along with the bronchoscopic modalities used. The primary outcome was the diagnostic yield with the addition of the GenCut TBNA, and the key secondary outcome was the complication rate.RESULTS: Of the 324 nodule biopsies analyzed, 164 (50.6%) were diagnostic via TBBx or GenCut TBNA. In all, 97 (59%) were positive in both TBBx and GenCut TBNA, 43 (26.2%) were positive only in TBBx, and 24 (14.6%) were positive only in GenCut TBNA. Overall, the addition of the GenCut TBNA increased the diagnostic yield by 7.4% (P<0.01). There were 7 complications: 5 pneumothoraxes and 2 episodes of bleeding.All authors: Anderson ED, DeBrito P, Krochmal R, Orr L, Sonti ROriginally published: Journal of Bronchology & Interventional Pulmonology. 29(2):140-145, 2022 Apr 01.Fiscal year: FY2022Digital Object Identifier: Date added to catalog: 2022-05-11
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 35318988 Available 35318988

BACKGROUND: Pulmonary nodules are increasingly detected on screening and routine chest imaging, leading to an increase in diagnostic procedures. Bronchoscopy with transbronchial biopsy (TBBx) is the most common diagnostic modality, with diagnostic yield between 43% and 86%, largely dependent on the use of navigational modalities. In 2015 a new biopsy tool by Medtronic, the GenCut core biopsy system [GenCut transbronchial needle aspiration (TBNA)], was developed with the intention of improving yield in lung nodule biopsies. Our goal was to determine the efficacy of this new device when used in addition to TBBx.

CONCLUSION: The diagnostic yield is improved by using the GenCut core biopsy system in addition to traditional TBBx forceps when performing bronchoscopy for pulmonary nodules, without an increase in complications. These biopsy methods should be used in tandem for the greatest yield. Copyright ♭ 2021 Wolters Kluwer Health, Inc. All rights reserved.

PATIENTS AND METHODS: This is a prospective observational study of 324 consecutive bronchoscopic lung biopsies in which both TBBx and GenCut TBNA were performed on the same lesion. We recorded patient and nodule characteristics, along with the bronchoscopic modalities used. The primary outcome was the diagnostic yield with the addition of the GenCut TBNA, and the key secondary outcome was the complication rate.

RESULTS: Of the 324 nodule biopsies analyzed, 164 (50.6%) were diagnostic via TBBx or GenCut TBNA. In all, 97 (59%) were positive in both TBBx and GenCut TBNA, 43 (26.2%) were positive only in TBBx, and 24 (14.6%) were positive only in GenCut TBNA. Overall, the addition of the GenCut TBNA increased the diagnostic yield by 7.4% (P<0.01). There were 7 complications: 5 pneumothoraxes and 2 episodes of bleeding.

English

Powered by Koha