MedStar Authors catalog › Details for: Transcranial Doppler velocity and associations with delayed cerebral ischemia in aneurysmal subarachnoid Hemorrhage.
Normal view MARC view ISBD view

Transcranial Doppler velocity and associations with delayed cerebral ischemia in aneurysmal subarachnoid Hemorrhage.

by Chang, Jason J; Triano, Matthew; Corbin, Maite J; Desale, Sameer; Liu, Ai-Hsi; Felbaum, Daniel R; Mai, Jeffrey C; Armonda, Rocco A; Aulisi, Edward.
Citation: Journal of the Neurological Sciences. 415:116934, 2020 May 20..Journal: Journal of the neurological sciences.Published: ; 2020ISSN: 0022-510X.Full author list: Chang JJ; Triano M; Corbin MJ; Desale S; Liu AH; Felbaum DR; Mai JC; Armonda RA; Aulisi EF.UI/PMID: 32526525.Subject(s): IN PROCESS -- NOT YET INDEXEDInstitution(s): MedStar Washington Hospital Center | MedStar Heart & Vascular InstituteDepartment(s): Surgery/Surgical Critical Care | Radiology | NeurosurgeryActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: (Click here) Abbreviated citation: J Neurol Sci. 415:116934, 2020 May 20.Abstract: BACKGROUND AND PURPOSE: We evaluated optimal transcranial Doppler (TCD) measures for predicting delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH).Abstract: MATERIAL AND METHODS: Consecutive patients with aSAH and daily middle cerebral artery (MCA) TCD recordings were retrospectively analyzed. Change in TCD velocity was obtained by creating a smoothing curve. Change in TCD velocity was determined with a linear regression model that confirmed greatest change in velocity associated with DCI occurred at days 2-7. Multivariate logistic regression analysis was then completed.Abstract: RESULTS: 95 patients were evaluated. Increase in TCD velocity at days 2-7 proved to be the best predictor for DCI with an optimal cutoff of 8.9 cm/s/day (p = .019) and AUC 0.651. Multivariate logistic regression analysis using DCI as outcome showed that poor admission Hunt-Hess scores (OR 5.02, 95%CI 1.22-22.67, p = .028) and increases in TCD velocity (OR 5.32, 95%CI 1.41-23.33, p = .018) were independently associated with DCI.Abstract: CONCLUSIONS: We found that relative increases in TCD velocities in the MCAs during the first 7 days (with a threshold increase of 53.4 cm/s from days 2 to 7) after aSAH admission were independently associated with DCI. This association requires independent confirmation. Copyright (c) 2020 Elsevier B.V. All rights reserved.

Powered by Koha