Citation: European Radiology. 22(6):1287-94, 2012 Jun..Journal: European radiology.ISSN: 0938-7994.Full author list: Utsunomiya D; Weigold WG; Weissman G; Taylor AJ.UI/PMID: 22200900.Subject(s): Adult | Aged | *Algorithms | Cardiac-Gated Imaging Techniques | *Coronary Angiography/mt [Methods] | *Coronary Artery Disease/ra [Radiography] | Female | Humans | Male | Middle Aged | Radiographic Image Enhancement/mt [Methods] | *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] | Reproducibility of Results | Sensitivity and Specificity | *Tomography, X-Ray Computed/mt [Methods] | Young AdultInstitution(s): MedStar Health Research Institute | MedStar Heart & Vascular InstituteActivity type: Journal Article.Medline article type(s): Journal ArticleAbbreviated citation: Eur Radiol. 22(6):1287-94, 2012 Jun.Abstract: OBJECTIVES: To evaluate the effect of hybrid iterative reconstruction on qualitative and quantitative parameters at 256-slice cardiac CT.Abstract: METHODS: Prospective cardiac CT images from 20 patients were analysed. Paired image sets were created using 3 reconstructions, i.e. filtered back projection (FBP) and moderate- and high-level iterative reconstructions. Quantitative parameters including CT-attenuation, noise, and contrast-to-noise ratio (CNR) were determined in both proximal- and distal coronary segments. Image quality was graded on a 4-point scale.Abstract: RESULTS: Coronary CT attenuation values were similar for FBP, moderate- and high-level iterative reconstruction at 293 +/- 74-, 290 +/- 75-, and 283 +/- 78 Hounsfield units (HU), respectively. CNR was significantly higher with moderate- and high-level iterative reconstructions (10.9 +/- 3.5 and 18.4 +/- 6.2, respectively) than FBP (8.2 +/- 2.5) as was the visual grading of proximal vessels. Visualisation of distal vessels was better with high-level iterative reconstruction than FBP. The mean number of assessable segments among 289 segments was 245, 260, and 267 for FBP, moderate- and high-level iterative reconstruction, respectively; the difference between FBP and high-level iterative reconstruction was significant. Interobserver agreement was significantly higher for moderate- and high-level iterative reconstruction than FBP.Abstract: CONCLUSIONS: Cardiac CT using hybrid iterative reconstruction yields higher CNR and better image quality than FBP.Abstract: KEY POINTS: * Cardiac CT helps clinicians to assess patients with coronary artery disease * Hybrid iterative reconstruction provides improved cardiac CT image quality * Hybrid iterative reconstruction improves the number of assessable coronary segments * Hybrid iterative reconstruction improves interobserver agreement on cardiac CT.