TY - BOOK AU - Dewey, Kayla AU - Mazer-Amirshahi, Maryann TI - Trends in opioid analgesic use for headaches in US emergency departments SN - 0735-6757 KW - *Analgesics, Opioid/tu [Therapeutic Use] KW - *Emergency Service, Hospital/td [Trends] KW - *Headache/dt [Drug Therapy] KW - Adolescent KW - Adult KW - Aged KW - Analgesics/tu [Therapeutic Use] KW - Female KW - Health Care Surveys KW - Humans KW - Male KW - Middle Aged KW - Retrospective Studies KW - United States/ep [Epidemiology] KW - Young Adult KW - MedStar Washington Hospital Center KW - Emergency Medicine KW - Journal Article N1 - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 N2 - CONCLUSIONS: Despite limited endorsement by consensus guidelines, there was increased use of opioid analgesics to treat headaches in US EDs over the past decade.Copyright � 2014 Elsevier Inc. All rights reserved; METHODS: We performed a retrospective review of the National Hospital Ambulatory Medical Care Survey, 2001 through 2010. Adult headache-related visits were identified. Medications (opioid and nonopioid) used for the treatment of headache were categorized based on medication class. Trends in ED use of the most common opioids (codeine, hydrocodone, hydromorphone, morphine, and oxycodone) were explored. The proportion of visits for which each medication was used was tabulated, and trends were analyzed using survey-weighted logistic regression; OBJECTIVE: Although not recommended as first line therapy by consensus guidelines, opioid analgesics are commonly used to treat headaches. This study evaluates trends in opioid use for headaches in US emergency departments (EDs); RESULTS: Headache visits during which any opioid was used increased between 2001 (20.6%; 95% confidence interval [CI], 18.1-23.4) and 2010 (35.0%; 95% CI, 31.8-38.4; P < .001). Prescribing of hydromorphone, morphine, and oxycodone increased, with the largest relative increase (461.1%) in hydromorphone (2001, 1.8% [95% CI, 1.2-2.6]; 2010, 10.1% [95% CI, 8.2-12.4]). Codeine use declined, and hydrocodone use remained stable. Use of opioid alternatives, including acetaminophen, butalbital, and triptans did not change over the study period, whereas use of nonsteroidal anti-inflammatory drugs increased from 26.2% (95% CI, 23.0-29.7) to 31.4% (95% CI, 28.6-34.3). Prescribing of antiemetic agents decreased from 24.1% (95% CI, 19.6-29.2) to 23.5% (95% CI, 21.1-26.0). Intravenous fluid use increased from 20.0% (95% CI, 17.0-23.4) to 34.5% (95% CI, 31.0-38.2) of visits UR - http://dx.doi.org/10.1016/j.ajem.2014.07.001 ER -