TY - BOOK AU - Manvar, Sohilkumar AU - Mohamad, Tamam AU - Panaich, Sidakpal S AU - Patel, Darshan AU - Patel, Jay TI - Trends of Hospitalizations in the United States from 2000 to 2012 of Patients >60 Years With Aortic Valve Disease SN - 0002-9149 KW - *Heart Defects, Congenital/di [Diagnosis] KW - *Heart Defects, Congenital/th [Therapy] KW - *Heart Valve Diseases/di [Diagnosis] KW - *Heart Valve Diseases/th [Therapy] KW - *Hospital Mortality/td [Trends] KW - *Hospitalization/td [Trends] KW - Aged KW - Aged, 80 and over KW - Aortic Valve KW - Aortic Valve Stenosis/di [Diagnosis] KW - Aortic Valve Stenosis/th [Therapy] KW - Cost of Illness KW - Female KW - Heart Defects, Congenital/ec [Economics] KW - Heart Defects, Congenital/mo [Mortality] KW - Heart Valve Diseases/ec [Economics] KW - Heart Valve Diseases/mo [Mortality] KW - Hospitalization/ec [Economics] KW - Humans KW - Male KW - Middle Aged KW - Risk Assessment KW - Risk Factors KW - United States KW - MedStar Heart & Vascular Institute N1 - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 N2 - In recent years, there has been an increased emphasis on the diagnosis and treatment of valvular heart disease and, in particular, aortic stenosis. This has been driven in part by the development of innovative therapeutic options and by an aging patient population. We hypothesized an increase in the number of hospitalizations and the economic burden associated with aortic valve disease (AVD). Using Nationwide Inpatient Sample from 2000 to 2012, AVD-related hospitalizations were identified using International Classification of Diseases, Ninth Revision, Clinical Modification, code 424.1, as the principal discharge diagnosis. Overall AVD hospitalizations increased by 59% from 2000 to 2012. This increase was most significant in patients >80 years and those with higher burden of co-morbidities. The most frequent coexisting conditions were hypertension, heart failure, renal failure, anemia, and diabetes. Overall inhospital mortality of patients hospitalized for AVD was 3.8%, which significantly decreased from 4.5% in 2000 to 3.5% in 2012 (p <0.001). The largest decrease in mortality was seen in the subgroup of patients who had heart failure (62% reduction), higher burden of co-morbidities (58% reduction), and who were >80 years (53% reduction). There was a substantial increase in the cost of hospitalization in the last decade from UR - http://dx.doi.org/10.1016/j.amjcard.2015.03.053 ER -