Evaluation and Treatment of Primary Spinal Epidural Lymphoma Presenting as Acute Myelopathy in a Young Adult: A Case Report. 

 -  2023 
<br/><br/> CASE: Primary spinal epidural lymphoma (PSEL) presenting as myelopathy is extremely rare, particularly within young, healthy adults. This case report describes a 26-year-old man presenting with progressive thoracic myelopathy. Magnetic resonance imaging revealed spinal epidural masses spanning T5-T10 and T12-L2 with multilevel cord compression and edema. After evaluation, the patient underwent emergent posterior decompression to prevent progressive neurological decline. Histology was consistent with diffuse large B-cell lymphoma, germinal center type. At 3 months postoperatively, the patient regained full neurologic function.  CONCLUSION: Although rare, PSELs should be considered in patients presenting with myelopathy to facilitate timely diagnosis and treatment. Copyright © 2023 by The Journal of Bone and Joint Surgery, Incorporated. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>2160-3251 
<br/><br/><label>Standard No.: </label>01709767-202309000-00057 [pii] 10.2106/JBJS.CC.23.00111 [doi] 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*Bone Marrow Diseases<br/>*Lymphoma, Large B-Cell, Diffuse<br/>*Musculoskeletal Diseases<br/>*Spinal Cord Compression<br/>*Spinal Cord Diseases<br/>Adult<br/>Humans<br/>Lymphoma, Large B-Cell, Diffuse/co [Complications]<br/>Lymphoma, Large B-Cell, Diffuse/dg [Diagnostic Imaging]<br/>Male<br/>Spinal Cord Compression/dg [Diagnostic Imaging]<br/>Spinal Cord Compression/et [Etiology]<br/>Spinal Cord Compression/su [Surgery]<br/>Young Adult--Automated
<br/><br/><label>Subjects--Geographic Terms: </label><br/>MedStar Southern Maryland Hospital
<br/><br/><label>Index Terms--Occupation: </label><br/>MedStar Georgetown University Hospital/MedStar Washington Hospital Center<br/>Orthopaedic Surgery Residency
<br/><br/><label>Index Terms--Function: </label><br/>Case Reports<br/>Journal Article