Risk of post-tonsillectomy hemorrhage among COVID-19 positive pediatric patients. 

 -  2024 
<br/><br/> CONCLUSION: The results of this investigation suggest that the presence of COVID-19 in the perioperative period may pose an increased risk for acute or delayed post tonsillectomy hemorrhage. This study employed a large, diverse population and is the first to address this clinical question. Copyright © 2024. Published by Elsevier B.V.  METHODS: The TriNetX database was queried for pediatric patients who underwent tonsillectomy and evaluated for outcomes of primary and secondary post-tonsillectomy hemorrhage.  OBJECTIVE: COVID-19 infection has been demonstrated to increase risk for post-operative bleeding. This study investigated the impact of COVID-19 infection on post-tonsillectomy hemorrhage in pediatric patients, a potentially devastating complication.  RESULTS: Among subjects 18 years and younger, 1226 were COVID-19 positive and 38,241 were COVID-19 negative in the perioperative period. There was statistically significant increased risk of bleeding with perioperative COVID-19 infection at postoperative days 1, 5, and 10. Additionally, when assessing the role of COVID-19 infection before or after surgery, the risk of bleeding remained statistically significant at all three time points, however these results did not suggest that infection before surgery confers more/less risk compared to infection after.  STUDY DESIGN: Retrospective cohort study. 
<br/><br/><br/>English 
<br/><br/><label>ISSN: </label>0165-5876 
<br/><br/><label>Standard No.: </label>S0165-5876(24)00044-2 [pii] 
<br/><br/><label>Subjects--Topical Terms: </label><br/>*COVID-19<br/>*Tonsillectomy<br/>Child<br/>COVID-19/co [Complications]<br/>Humans<br/>Postoperative Hemorrhage/ep [Epidemiology]<br/>Postoperative Hemorrhage/et [Etiology]<br/>Postoperative Period<br/>Retrospective Studies<br/>Tonsillectomy/ae [Adverse Effects]<br/>Tonsillectomy/mt [Methods]--Automated
<br/><br/><label>Index Terms--Occupation: </label><br/>MedStar Georgetown University Hospital/MedStar Washington Hospital Center<br/>Otolaryngology Residency
<br/><br/><label>Index Terms--Function: </label><br/>Journal Article