TY - BOOK AU - Swain, Sandra M TI - 6th and 7th International consensus guidelines for the management of advanced breast cancer (ABC guidelines 6 and 7) SN - 0960-9776 PY - 2024/// KW - *Breast Neoplasms KW - *Palliative Care KW - Breast Neoplasms/pa [Pathology] KW - Breast Neoplasms/th [Therapy] KW - Consensus KW - Female KW - Humans KW - Palliative Care/st [Standards] KW - Practice Guidelines as Topic KW - Automated KW - Associate Dean for Research Development KW - MedStar Health KW - Journal Article KW - Practice Guideline N2 - This manuscript describes the Advanced Breast Cancer (ABC) international consensus guidelines updated at the last two ABC international consensus conferences (ABC 6 in 2021, virtual, and ABC 7 in 2023, in Lisbon, Portugal), organized by the ABC Global Alliance. It provides the main recommendations on how to best manage patients with advanced breast cancer (inoperable locally advanced or metastatic), of all breast cancer subtypes, as well as palliative and supportive care. These guidelines are based on available evidence or on expert opinion when a higher level of evidence is lacking. Each guideline is accompanied by the level of evidence (LoE), grade of recommendation (GoR) and percentage of consensus reached at the consensus conferences. Updated diagnostic and treatment algorithms are also provided. The guidelines represent the best management options for patients living with ABC globally, assuming accessibility to all available therapies. Their adaptation (i.e. resource-stratified guidelines) is often needed in settings where access to care is limited. Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved UR - https://dx.doi.org/10.1016/j.breast.2024.103756 ER -