TY - BOOK AU - Lindsey, Sierra AU - McKinstry, Robert AU - Strickland, Paige AU - Tarapore, Rae TI - Demonstrating antibiotic stewardship while diagnosing and treating bilateral pseudoseptic arthritis: a case report SN - 1752-1947 PY - 2024/// KW - *Anti-Bacterial Agents KW - *Antimicrobial Stewardship KW - Anti-Bacterial Agents/tu [Therapeutic Use] KW - Anti-Inflammatory Agents, Non-Steroidal/tu [Therapeutic Use] KW - C-Reactive Protein/an [Analysis] KW - Female KW - Humans KW - Knee Joint KW - Middle Aged KW - Osteoarthritis, Knee/dt [Drug Therapy] KW - Treatment Outcome KW - Viscosupplementation KW - Curated KW - MedStar Union Memorial Hospital KW - Orthopaedic Surgery KW - Orthopaedic Surgery Residency KW - Case Reports KW - Journal Article N1 - Available online through MWHC library: 2007 - present N2 - CASE PRESENTATION: In this case report, we present a 61-year-old African American female patient who presented with bilateral knee pseudoseptic arthritis in the setting of viscosupplementation. She presented 3 days after bilateral viscosupplementation injections with bilateral knee swelling, discomfort, and pain with micromotion. Her white blood cell count (WBC) was 12.83 (4.5-11 normal), her C-reactive protein (CRP) level was 159 mg/L (0-10 normal), and her erythrocyte sedimentation rate (ESR) was 79 mm/hour (0-40 normal). Her left knee aspirate yielded 38,580 WBC with a negative gram stain and negative cultures. Her right knee aspirate yielded 29,670 WBC with a negative gram stain and negative cultures. Through the utilization of careful clinical monitoring, ice therapy, and non-steroidal inflammatory medication, we were able to successfully treat this patient while maintaining proper antibiotic stewardship; CONCLUSION: Pseudoseptic arthritis in the setting of viscosupplementation can be adequately treated and monitored without the use of antibiotics. Copyright © 2024. The Author(s); INTRODUCTION: Although viscosupplementation is a commonly used treatment for osteoarthritis and is widely regarded as a safe treatment option, it is associated with the rare complication of pseudoseptic arthritis. Most existing case reports that cite this rare complication employed the use of early broad-spectrum antibiotics UR - https://dx.doi.org/10.1186/s13256-024-04568-2 ER -