TY  - BOOK
AU  - Stewart, Diana
TI  - Symptom management challenges in heart failure: pharmacotherapy considerations. [Review]
SN  - 1382-4147
PY  - 2017///
KW  - *Cardiovascular Agents/tu [Therapeutic Use]
KW  - *Drug Monitoring/mt [Methods]
KW  - *Heart Failure/dt [Drug Therapy]
KW  - *Palliative Care/mt [Methods]
KW  - *Quality of Life
KW  - Humans
KW  - United States
KW  - MedStar Washington Hospital Center
KW  - Pharmacy
KW  - Journal Article
KW  - Review
N1  - Available online from MWHC library: 1997 - present; Available online from MWHC library: 1997 - present
N2  - Heart failure is a chronic, progressive illness that is increasing in prevalence in the USA. Patients with advanced heart failure experience a high symptom burden that is comparable to patients with advanced cancer. Palliative care, however, is underutilized in patients with heart failure, and symptoms may go untreated as the disease progresses. A combination of pharmacologic and non-pharmacologic interventions should be used to address symptoms and maintain quality of life. While there have been significant advances in evidence-based heart failure treatments in recent years, selection of appropriate palliative medications as symptoms progress is challenging due to limited clinical studies in this patient population. Medications that are commonly used for symptom management in other life-limiting illnesses may have little to no evidence in heart failure, or have undesirable cardiac effects that preclude use. Clinicians must extrapolate available clinical evidence and prescribing considerations relevant to heart failure to palliate symptoms as well as possible. The objectives of this paper are to review the most common and distressing symptoms in heart failure, analyze evidence, or lack thereof, for pharmacologic management of symptoms, and provide prescribing considerations based on side effect profiles and comorbid conditions
UR  - https://dx.doi.org/10.1007/s10741-017-9632-5
ER  -