TY - BOOK AU - Giladi, Aviram M AU - Harbour, Patrick AU - Zimmerman, Ryan M TI - Delayed Digit Replantation: What is the Evidence?. [Review] SN - 0363-5023 PY - 2021/// KW - *Amputation, Traumatic KW - *Finger Injuries KW - Amputation KW - Amputation, Traumatic/su [Surgery] KW - Finger Injuries/su [Surgery] KW - Fingers/su [Surgery] KW - Humans KW - Replantation KW - Curtis National Hand Center KW - MedStar Georgetown University Hospital KW - Plastic Surgery Residency KW - Journal Article KW - Review N2 - A persistent challenge that has limited access and delivery of digit replantation surgery is timing, as ischemia time has traditionally been considered an important determinant of success. However, reports that the viability of amputated digits decreases after 6 hours of warm ischemia and 12 hours of cold ischemia are largely anecdotal. This review evaluates the quality and generalizability of available evidence regarding ischemia times after digit amputation and reported outcomes of "delayed" replantation. We identify substantial limitations in the literature supporting ischemia time cutoffs and recent evidence supporting the feasibility of delayed digit replantation. The current treatment approach for amputation injuries often necessitates transfers or overnight emergency procedures that increase costs and limit availability of digit replantation nationwide. Evidence-based changes to digit replantation protocols could lead to broader availability of this service, as well as improved care quality. Copyright (c) 2021 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved UR - https://dx.doi.org/10.1016/j.jhsa.2021.07.007 ER -