TY - BOOK AU - Badr, Salem AU - Fatemi, Omid AU - Kitabata, Hironori AU - Minha, Sa'ar AU - Pichard, Augusto D AU - Satler, Lowell F AU - Suddath, William O AU - Torguson, Rebecca AU - Waksman, Ron TI - Safety and long-term outcomes after percutaneous coronary intervention in patients with human immunodeficiency virus. [] SN - 1522-1946 PY - 2015/// KW - *Coronary Artery Disease/th [Therapy] KW - *HIV Infections/co [Complications] KW - *Percutaneous Coronary Intervention KW - Aged KW - Chi-Square Distribution KW - Coronary Artery Disease/co [Complications] KW - Coronary Artery Disease/di [Diagnosis] KW - Coronary Artery Disease/mo [Mortality] KW - Databases, Factual KW - Drug-Eluting Stents KW - Female KW - HIV Infections/di [Diagnosis] KW - HIV Infections/mo [Mortality] KW - Humans KW - Kaplan-Meier Estimate KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Myocardial Infarction/et [Etiology] KW - Odds Ratio KW - Patient Selection KW - Percutaneous Coronary Intervention/ae [Adverse Effects] KW - Percutaneous Coronary Intervention/is [Instrumentation] KW - Percutaneous Coronary Intervention/mo [Mortality] KW - Proportional Hazards Models KW - Retrospective Studies KW - Risk Assessment KW - Risk Factors KW - Time Factors KW - Treatment Outcome KW - MedStar Heart & Vascular Institute KW - Journal Article KW - Observational Study N1 - Available online from MWHC library: 1996 - present, Available in print through MWHC library: 1996 - 2006 N2 - BACKGROUND: Sparse data exists regarding the risk of patients with HIV who undergo PCI; CONCLUSION: PCI in HIV+ patients is safe, with high procedural success rates, and produces similar outcomes to those seen in HIV- patients at 2 years. HIV+ patients should be treated with DES if possible.Copyright � 2014 Wiley Periodicals, Inc; METHODS: Using a case-control design, we compared baseline characteristics, procedure-related outcomes, in-hospital, and 2-year clinical outcomes of 112 consecutive HIV+ patients versus 112 HIV- controls matched for age, gender, and diabetes mellitus who underwent PCI from April 2003 to September 2011; OBJECTIVE: This study aims to report the long-term outcomes after percutaneous coronary intervention (PCI) in human immunodeficiency virus (HIV+) patients; RESULTS: Baseline characteristics were generally comparable, save for more African Americans and history of chronic renal insufficiency in the HIV+ vs. HIV- group (62.5% vs. 21.4%, P < 0.001) and (27.7% vs. 9.9%, P < 0.001). There was no correlation between CD4 nadir count and extent and diffuseness of coronary artery disease. The occurrence of major adverse cardiac events at 2 years was similar in both groups. Multivariable analysis for independent correlates of major adverse cardiac events at 2 years detected patients with a history of chronic renal insufficiency (OR: 2.44, 95% confidence interval: 1.02-5.83; P = 0.04) and acute myocardial infarction (OR: 2.92, 95% confidence interval: 1.39-6.15; P = 0.005) as correlates for outcome. Post-hoc analysis showed that drug-eluting stent (DES) use in the HIV+ group was beneficial UR - http://dx.doi.org/10.1002/ccd.25466 ER -